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"AI will cure cancer" misunderstands both AI and medicine

rachel.fast.ai

111–120 of 207 posts

Re: "AI will cure cancer" misunderstands both AI and medicine

#111

Earlier quoted context omitted.

Cancer isn’t one thing and AI is an important tool that will accelerate treatment and drug development. My late wife detected a mole that was melanoma in 2019. She was within months of being cleared for observation in 2023 when two brain tumors were detected. Despite the best of care, she was gone in 6 months. If her initial treatment had been in 2024 instead of 2019, it’s 80% likely she would be around for another d…

Can you elaborate a little on what's new? Someone close to me had a melanoma scare on almost the same time frame, and had a lot of difficulty finding doctors who would take her seriously.

In the case of my wife, she would have been given a round of nivolumab or keytruda. These are immunotherapies that enable your immune system to kill the cancer cells.

You have to advocate very heavily. With melanoma, I wouldn’t mess around and seek at a minimum second opinions from the nearest major cancer center.

Re: "AI will cure cancer" misunderstands both AI and medicine

#112

The article completely misses the essential mechanism behind the advancement of science, like cures for disease. Advancing science is not about making better use of the info you have. It's about gathering NEW info you didn't have before and then using it to propose a novel mechanism of action or a hypothesis leading to a better theory. But AI cannot gather new info. Only better sensors can do that. Without gathering…

…Alphafold?

Re: "AI will cure cancer" misunderstands both AI and medicine

#113

Saying you'll cure cancer with AI without specifying the type of cancer is like declaring you'll solve crime with Batman. Way too broad to be useful, but makes a good headline.

And likewise without specifying the type of AI.

Asking Stable Diffusion for a picture of the chemical structure of a drug to cure even one specific unsolved cancer… I'd be surprised if that ever works (but given how crazy the rate of change has been, only 2σ of surprise).

Re: "AI will cure cancer" misunderstands both AI and medicine

#114
post #101

I have the utmost respect for the work that Jeremy and team and Fast.ai have accomplished but in this post Rachel is railing against the free market, bugs in software and preexisting biases in humans to create an incredibly cynical and unrelated cocktail. There are many things broken about our world. We should work hard to fix them. But the promise of AI as a research tool to create the kinds of breakthroughs that hu…

Rachel and I are well aware of the promise of AI as a research tool. I created the first company that focussed on deep learning in medicine. Rachel has a PhD in math and is now doing a masters in immunology, and is trying to help figure out to bring AI to medical research. The point of the article is that AI as a research tool is insufficient to result in improvements to patient outcomes on its own. The article inclu…

Thanks Jeremy. Makes sense. What you all have accomplished is incredible, particularly in democratizing AI via your learning materials. Fast.ai is required learning for our team.

Re: "AI will cure cancer" misunderstands both AI and medicine

#115
post #5

Saying "AI will cure cancer" is like saying "science will cure cancer" or "doctors will cure cancer". In general, all three statements are true about technological progress. > Second, AI is used to disproportionately benefit the privileged while worsening inequality. That's bullshit. Computers and other gadgets always start out as toys of the rich, but they quickly trickle down to everyone else. Compare the multi-tho…

Technology is an amoral form of power that accrues to those who have access to it, as well as have the most access to it. In unequal societies, this accrual is to those who already have wealth, political power, etc. If the opposite was true, as you claim, the most technologically advanced countries would have seen decreasingly inequality in the period you fit. In reality, they’ve only seen the opposite.

It is because your view of inequality is bullshit. Your views are exactly in line with Khmer Rogue.

Cambodia in 1977 was a much more equal society than America in 2024. Can't argue with that.

Re: "AI will cure cancer" misunderstands both AI and medicine

#116
post #66
post #58

Earlier quoted context omitted.

No, you're the one who doesn't understand AI. At this point AI has demonstrated ample capability to extrapolate to out of sample data.

Also known as hallucination

No, hallucinations are specifically when they make mistakes, even when they're more like interpolation than extrapolation.

IIRC, it became a term of art during image classification AI development, where an AI might confidently assert a car was a potato, and the name stuck.

Re: "AI will cure cancer" misunderstands both AI and medicine

#117
post #77

Earlier quoted context omitted.

Yeah that’s wild! I do think proactive medical screening is something most medical systems have mostly given up on, other than in very targeted ways, for very specific diseases in very specific high risk populations. But I don’t think this is because it’s a fundamentally bad idea, I think it’s more that it’s impractical right now. It does seem to me that AI has a chance to make it practical.

If you screen a lot of people for a lot of things, you will find a lot of things, but not all the findings will mean something or require action. The initial ramp up of huge "unwarranted" screenings will create a lot of pain until we/AI figures out when something warrants attention.

Can't we intelligently limit that to things with essentially no risk of false positive?

Re: "AI will cure cancer" misunderstands both AI and medicine

#119

Earlier quoted context omitted.

I kind of feel like that's exactly why AI is helpful here: - Grab a cancer (or virus, bacteria, etc.) - Sequence it - AI will develop a custom therapy for that cancer In broad strokes, it's not hard to develop a therapy for any specific cancer or other disease in a specific individual. There are several broad strategies: - A targeted, custom phage to kill a bacteria (or extrapolate to killing a type of cells) - A cus…

It sounds so easy maybe you could be so kind and write a few lines of codes and finally cure cancer

Reminds me of this: https://youtu.be/tNfGyIW7aHM?si=vS4vlmD0mufCv0Cw

Re: "AI will cure cancer" misunderstands both AI and medicine

#120
post #106

"There is already a clear pattern in which AI is used to centralize power and harm the marginalized." Too bad this was in the last paragraph or so, it could've spared me from reading the rest if it was in the beginning.

In fairness "AI is used to disproportionately benefit the privileged while worsening inequality" was near the beginning.

Not the best article really.

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