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Anti-aging drug for dogs moves closer to gaining FDA approval

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Re: Anti-aging drug for dogs moves closer to gaining FDA approval

#111

Post by carstenhag »

ornornor wrote: post #80
carstenhag wrote: post #62

Earlier quoted context omitted.

Isn't it very important to have at least 2 cats, when they are indoors? I was told this by a vet.

I think this depends more on your lifestyle. If you're never home and can't play with your cat, there is nothing to watch out of the windows (birds, nature...), no toys, etc then I guess two cats make sense because they can entertain each other. But otherwise, it's fine. We were feeling guilty about keeping our cat indoors after the incident (it's not in their nature, etc) but every (North American) vet told us that…

This was in Europe and I was working from home during that time. We only had one cat. I played with it for sure, but not for hours. He had a window. Made weird sounds, especially at night. Once we got the second cat it was much better, at least to us he seemed way more chill.

Re: Anti-aging drug for dogs moves closer to gaining FDA approval

#112

Post by stronglikedan »

digging wrote: post #92
stronglikedan wrote: post #68

Earlier quoted context omitted.

It doesn't matter. It doesn't make it any less true. I really wish politics didn't dominate everything lately.

But Fox News is an untrustworthy source known for intentionally spreading misinformation, even if it mostly reports true things. This piece probably is true but I actually wouldn't take anything from them without a second (ideally, primary) source.

So is CNN, and every other outlet, unfortunately. But for stories like this with no political motivation, any outlet can be trusted just as much as any other, so it doesn't matter which is reporting it.

Re: Anti-aging drug for dogs moves closer to gaining FDA approval

#114

Post by idopmstuff »

Empact wrote: post #44
ScottEvtuch wrote: post #37

Earlier quoted context omitted.

That doesn't really follow. I have the legal authority to pay a junk yard to smash my car into a tiny cube, but that doesn't mean I shouldn't be protected from auto body shops selling me fake repairs and non-functional parts.

Are we making a good trade-off if that protection means preventing lifesaving treatments from reaching the market for decades or more? Does the risk the part might not work somehow justify the loss of life due to the absence of a lifesaving treatment? Wouldn’t we learn a lot more about the effects of these experimental treatments if we allowed the willing to take them voluntarily?

> Wouldn’t we learn a lot more about the effects of these experimental treatments if we allowed the willing to take them voluntarily?

In the case of life-extension treatments, no - we would learn much less if we allowed people to give them to their pets voluntarily.

The problem is that what you're testing for is very difficult to measure, so you need a well-run study like the one that Loyal has done here. If people just give them to their dogs without the structure of a trial, you'll never get the kind of data you need to conclusive prove life-extending effects, and because companies can now sell without such a trial, you eliminate the incentives to invest the time, money and effort into that kind of a trial.

Re: Anti-aging drug for dogs moves closer to gaining FDA approval

#115

Post by lukev »

ryandvm wrote: post #104
lukev wrote: post #85

Earlier quoted context omitted.

There is absolutely nothing wrong with a well trained and socialized pit bull/mix. Anyone who says otherwise is lying to you or themselves. EDIT: None of the papers folks have posted control for training or socialization. I grant you that due to socioeconomic factors you will in fact find more samples of aggressive pitbulls than aggressive dogs of other breeds in most regions, but that is not what's under discussion.…

Disagree. I've had dogs all my life - many breeds. We currently have a rescue that is a pit/lab mix and although she is sweet as could be to humans, she is a menace at the dog park or day care. Constantly trying to fight. Folks who say that breeds don't matter are deluding themselves. Pits are just plain aggressive. There's a reason that every time you see a "DOG MAULS CHILD" headline, it's always one of the same few…

I’ve had numerous rescues as well, over my life, and this tends to be generally true for all breeds. The defining feature of a rescue is that they were not trained and socialized well.

Re: Anti-aging drug for dogs moves closer to gaining FDA approval

#116

Post by lukev »

nradov wrote: post #106
lukev wrote: post #85

Earlier quoted context omitted.

There is absolutely nothing wrong with a well trained and socialized pit bull/mix. Anyone who says otherwise is lying to you or themselves. EDIT: None of the papers folks have posted control for training or socialization. I grant you that due to socioeconomic factors you will in fact find more samples of aggressive pitbulls than aggressive dogs of other breeds in most regions, but that is not what's under discussion.…

I don't believe you. Most of those dogs are fine, but a few just seem to have a screw loose in a way that can't be fixed through training or socialization. People who believe otherwise are in denial or lack experience. Whether the root cause is due to irresponsible breeding or whatever is irrelevant, it's just really antisocial behavior to bring a pitbull where they can potentially present a risk to others. Think thr…

Everything you say applies to all large breeds. Judge a dog based on its owners and behavior.

Don’t judge someone just because they own a pitbull. The breed isn’t the fundamental problem.

Re: Anti-aging drug for dogs moves closer to gaining FDA approval

#117

Post by boppo1 »

Der_Einzige wrote: post #100
boppo1 wrote: post #63

Earlier quoted context omitted.

Good move unless it includes pit bull. Pitbull mixes are not appropriate for family pets and anyone who says otherwise is lying to you or themselves. Please protect your loved ones and stay away from pitbulls and pitbull mixes. They are total sweet hearts, right up until they're not. Edit: I too was once a 'how it's raised' apologist. After a number of experiences and some research, my mind is concluded. Someone in t…

I'll say it again and again - Pitbulls are black coded dogs and thus are treated like the black people of the dog world.

Comparing Black people to dogs literally bred for aggression is abhorrent. Pitbull apologism: dangerous and offensive!

Re: Anti-aging drug for dogs moves closer to gaining FDA approval

#118

Post by drakonka »

ornornor wrote: post #96
drakonka wrote: post #61

Earlier quoted context omitted.

Thank you, these are great tips. Sorry for your loss, sounds like you gave her a long and happy life. Luckily I already do all of these! (Except for dry food; we do wet and raw only here)

Thanks. It’s hard for people who haven’t gone through it to understand the pain it can cause. But even then, euthanasia is an act of compassion no matter how difficult it is rather than letting the animal suffer and slowly die. For dry food, vets told us some cats like it better but it also helps with oral health as it removes some of the plaque by friction and keeps the gums healthier by stimulating ligaments holdin…

I have not yet had to go through it myself, but came very close when one of my cats nearly died as a kitten. The experience affected me permanently and I get a little more anxious with every year that they get older.

From what I understand the plaque thing with dry food is a bit of a myth. After all, we don't brush our teeth by eating crackers. So I brush their teeth with a toothbrush and enzymatic toothpaste instead! For stimulating ligaments, that's really interesting. I feed largely a (balanced) homemade raw diet alongside commercial wet and suspect/hope having them chew through solid chunks of raw muscle meat would achieve a similar effect.

Re: Anti-aging drug for dogs moves closer to gaining FDA approval

#119

Post by HEmanZ »

crashmat wrote: post #90
HEmanZ wrote: post #34

Earlier quoted context omitted.

Comparing a family dog to a goldfish is such utter nonsense that you have to be a troll.

Humans can easily develop an emotional attachment to any living creature they care for, even things that aren't alive. Acting as if someone's emotional attachment to a creature is somehow invalid because it's not a creature people care about as often seems like more of the troll move here.

I’m totally on board with people loving their pets or anything else in the world important to them.

But the OPs comment was, to me at least, as absurd as if I said to someone “I don’t think you should worry so much about saving your daughter’s life. When I lost my dog, I was sad, but I got over it.”

These are not in the same category to most people, and you can’t assume your experience of losing a dog gives you insight into losing a child. Same goes with dog -> goldfish.

Re: Anti-aging drug for dogs moves closer to gaining FDA approval

#120

Post by ornornor »

drakonka wrote: post #118
ornornor wrote: post #96

Earlier quoted context omitted.

Thanks. It’s hard for people who haven’t gone through it to understand the pain it can cause. But even then, euthanasia is an act of compassion no matter how difficult it is rather than letting the animal suffer and slowly die. For dry food, vets told us some cats like it better but it also helps with oral health as it removes some of the plaque by friction and keeps the gums healthier by stimulating ligaments holdin…

I have not yet had to go through it myself, but came very close when one of my cats nearly died as a kitten. The experience affected me permanently and I get a little more anxious with every year that they get older. From what I understand the plaque thing with dry food is a bit of a myth. After all, we don't brush our teeth by eating crackers. So I brush their teeth with a toothbrush and enzymatic toothpaste instead…

It doesn’t replace brushing but as our cat was eating wet food with a sort of pâté consistency, it would accumulate in her teeth. Alternating this with dry food helped remove most of this still wet food from her teeth so that it doesn’t turn into stone as fast. It’ll never be as effective as brushing though but our cat didn’t allow it unfortunately.

If the wet food is chewy then I guess it’d be very similar to dry food. Our cat’s food consistency was softer so she’s need the hard kibbles to crunch on.

Losing a pet is never easy I think. Even if it isn’t human, it becomes a member of the family with its own character, habits, and behaviour. It does create a void when they go but it’s unfortunately inevitable. It’s difficult to know when is the right time, but I believe it’s worse to leave a pet suffer because its owner doesn’t have the empathy to call it.

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