Earlier quoted context omitted.
I mean, there's a reason ajax took off in the first place. Member having to reload the entire page on every user interaction? Member iframes? Member flash and silver light and java applets? With stuff like web sockets/Web rtc /whatever new awesome sauce is out today a lot of that has changed, but that's still really the same spirit of ajax anyway, just with actual persistent connections instead of hacking it with lon…
AJAX took off because it's good for interactivity. If your "AJAX" requests are literally blocking the functionality of the website then they're no better than returning a big HTML blob. Your page just takes longer to load and the user experience is worse.
Static HTML only has a potential latency benefit on first load due to the ability to save render-blocking resource roundtrips. For later requests where those resources are already fetched, it only adds bandwidth overhead.