We eat 5 times as much meat on average as people did 100 years go. Animal based products are a major source of fat. People used to eat more fruits and vegetables. The fat type has shifted with more fat (which has higher calorie per gram amounts than carbs or protein) and fat moving from polyunsaturated fats to saturated fats (which causes lots of medical problems).
In there is the growth hormone. Kids "mature" physically at younger ages now than they used to. Kids to stop stop dairy or a lot of mean may physically mature at the older slower pace.
Eating less fruits, vegetables, and whole grains means less fiber. Most people (in the US anyway) are deficient in fiber. Fiber traps certain fats and cholesterols so they aren't absorbed. So, we absorb more fats.
Then there are processed foods.
So much about our diets have changed in the last 100 years. A lot is known and we even know how to eat to be really healthy. It's just not widely known by the general public.