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First images of cerebrospinal fluid in the brain during sleep (2019)

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Re: First images of cerebrospinal fluid in the brain during sleep (2019)

#111

Earlier quoted context omitted.

Could you share a link to your work? I'd love to read more about it.

It's rather dated but my dissertation is saved for posterity [0] and includes references and old Octave code. [0] https://drive.google.com/file/d/1R4mS_4vzf5mycQez76O_mmpQDpT...

Thank you!

Re: First images of cerebrospinal fluid in the brain during sleep (2019)

#112
post #50

Very cool. I'd be very curious see if there are similar effects from basic meditation and/or from very advanced meditation in yogic or Buddhist traditions.

Hello! Because we see significant changes in CSF that can be induced by respiration, and meditation is known to decrease the frequency of respiration, I would expect there to be significant effects of CSF flow with meditation [1]. Beyond this, we know that with individuals who are good at meditating seem to induce theta waves in EEG [2]. Because there is a coupling between EEG/fMRI global hemodynamic signal/CSF flow,…

Indeed! And it might also be easier to test the various meditative states vs testing sleep states in such a machine...

Re: First images of cerebrospinal fluid in the brain during sleep (2019)

#113

This is curious. During my research into neutral networks we depended on a neuroscience result that found waves of trophic factor (i.e. the stuff used to build up neurons [i.e. learn]) travel in cascading waves from the core of the brain to the periphery. By adding a sense of location and a learning term contingent on the factor we saw learning (xor) prohibited by Minsky's result (not really prohibited because we cha…

Not what you asked -

I (no expert in neuroscience) had come across a neuroscience article in around 2004, which I could not find again, and on which I never came across anything else either. This said that myelination happens differently in different parts of the brain, culminating everywhere by adulthood. I had found that very interesting. If someone knows more about this, I would like to hear. :-)

Re: First images of cerebrospinal fluid in the brain during sleep (2019)

#114
post #3

Very cool. My daughter has a brain shunt due to complications of spina bifida and so we’re thinking of cerebrospinal fluid on a regular basis. As a layman I guess there’s a particular cerebrospinal fluid pressure you want, and that being too high or too low causes issues? Apparently the shunt just drains into her belly so I also found that interesting. Too high and she’ll have terrible headaches and an “alien” head (…

Too little CSF leads to the brain crushing itself under gravity. The brain is almost entirely lipids which contributes to its buoyancy in CSF. Take away too much CSF, nothing for it to float in. Too much CSF? The skull is a fixed volume (in adults) so the CSF compresses the brain tissue. In kids, the sutures or junctions between bones of the skull are still flexible. This allows for childbirth and normal rapid brain…

If there is too little CSF (e.g. a CSF leak), the brain 'slumps' but it doesn't "crush itself under gravity".

Too much CSF can lead to hydrocephalus, which is enlargement of the ventricles. I wouldn't describe it as CSF "compressing" the brain tissue.

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