Anarchists making their own medicine (2018)

> Oh. So you don't want a system that removes corruption, regulatory capture, and lobbying as far as possible?

Well, sure. But that's not what this is actually about. The titular anarchists are not inventing new drugs, they're finding alternative ways to get drugs that have already been invented.

> That is to say, with all else removed you could generate an IP only company for 17% the cost of drug sales.

I am not convinced that accurately reflects the reality of running a pharmaceutical business, even if incentives/competition is somewhat warped in healthcare. There are a lot of penny-stock pharma companies whose only mission is to generate valuable IP. They're notorious for being volatile (since their outcome is basically binary on the results of research), but not for being great investments. If what you are asserting was actually true, those sorts of firms would generate ~5x higher returns, on average.

At first I expected the advent of mass vaccination to end the pandemic, because it only had to drop R by a factor of two or so to drop below the critical percolation threshold, so even a vaccine providing 50% sterilizing immunity would be good enough, and the mRNA vaccines turned out to be even more effective than expected. I turned out to be spectacularly wrong about that; as you may or may not be aware, the pandemic did not end a year ago. It turned out that, unlike vaccines like the smallpox vaccine, the covid vaccines did not provide much sterilizing immunity.

Moreover, the virus has become endemic in a number of zoonotic reservoirs, including deer, feral cats, and some mustelids, and vaccinating or exterminating those populations is not realistic in the next few decades. This is not currently a significant source of human outbreaks as far as I can tell, but after the humans reach herd immunity, it will be the only one.

Consequently, the cost-benefit tradeoff for covid vaccinations with the currently available vaccines needs to be evaluated with respect to the benefit to the person being vaccinated. I'm glad I'm vaccinated: as an obese 45-year-old man, my risk of death from covid might approach 1%, which is enormously higher than any plausible risks from any of the vaccines I'm familiar with. But that tradeoff is not the same for everyone, and there are populations where the rate of death or permanent harm from a vaccine, though still extremely low, is likely higher than the rate of death or permanent harm from covid itself.

The situation would be different if, for example, vaccinating schoolchildren prevented them from infecting and inadvertently killing their grandparents. But it doesn't. So the fact that the existing vaccinations clearly fail to control the spread is extremely relevant to the cost-benefit tradeoff, in particular because it means that there's no valid public-interest argument for requiring people to get vaccinated. Since both the cost and the benefit flow to them individually, they should be able to make the decision individually, except in cases such as small children and comatose patients.

This is an argument that deserves rational consideration, not dismissal with mindkiller phrases like "vapors" and "anti-vax". That's the sort of argument, or rather non-argument, that "deserves to lose".

I can get the medicines I need to "save" me. I can't get the medicines that would help me to die. I wonder what this group's moral posture is on using their equipment to manufacture Nembutal (or other barbiturates).

I would like to have 15g of Nembutal in a safe place, so that I can kill myself painlessly and without leaving a mess, should the circumstances require that. I know that no medical professional would help me do that, because they would immediately be disqualified. Instead they would have to strive officiously to prolong my life.

Nembutal is illegal to possess, at least it is here. That's not like the drugs this group are helping people to make, which are all legal to possess provided you have a prescription, or so the article says. There's no "therapeutic" use for Nembutal that can't be met by a safer drug.

As a result Nembutal is really difficult to source (also because it's part of the traditional cocktail used in US death-by-poisoning executions).

>Well, sure. But that's not what this is actually about. The titular anarchists are not inventing new drugs, they're finding alternative ways to get drugs that have already been invented.

... yes and they're doing so because in part regulatory capture, lobbying, and corruption have lead to unaffordable drugs. So that is, partially, what this is actually about. But sure there are other reasons for people to manufacture their own drugs outside of formal channels.

>I am not convinced that accurately reflects the reality of running a pharmaceutical business, even if incentives/competition is somewhat warped in healthcare. There are a lot of penny-stock pharma companies whose only mission is to generate valuable IP. They're notorious for being volatile (since their outcome is basically binary on the results of research), but not for being great investments. If what you are asserting was actually true, those sorts of firms would generate ~5x higher returns, on average.

That's actually my point. Generating the IP looks to be low value compared to wading through all the insane regulatory barriers, developing sales channels in-bred with medical board licensed doctors and FDA regulators that examine sales materials, lobbying for regulatory capture and all the other expensive pursuits that arguably may not add much value to the ill person consuming the drug. Another words, I'm not sure removing IP from the equation really changes the cost of drugs that much.

You could be right; certainly you know a great deal more about the subject than I do.

What are the companies, or at least the industries, that would buy all the machines if you could make them much cheaper and/or better?