Back in 2011, there was an announcement from MIT about a new approach to a broad-spectrum antiviral that appeared to work.[1] This goes way beyond an AIDS-specific cure. But it was at MIT Lincoln Labs, which doesn't usually do bio. So the researcher moved to Draper Labs, but didn't get much funding. Then that funding ran out. Now the guy behind this is trying to get funding on Indiegogo.[3] The problem seems to be th…
It's suspicious that in 6 year he hasn't received any substantial funding. Anyways here is a link for donations: https://riderinstitute.org/pages/donate-to-draco-antiviral-r...
CRISPR eliminates HIV-1 infection in live animals
111–120 of 267 posts
Re: CRISPR eliminates HIV-1 infection in live animals
#112Back in 2011, there was an announcement from MIT about a new approach to a broad-spectrum antiviral that appeared to work.[1] This goes way beyond an AIDS-specific cure. But it was at MIT Lincoln Labs, which doesn't usually do bio. So the researcher moved to Draper Labs, but didn't get much funding. Then that funding ran out. Now the guy behind this is trying to get funding on Indiegogo.[3] The problem seems to be th…
Re: CRISPR eliminates HIV-1 infection in live animals
#113Earlier quoted context omitted.
> Right now HIV infections are basically a minor nuisance, provided you're taking the appropriate medication Even with your caveat, the fact that more than 1 million people died from HIV in 2015 is probably a good signal to not use the term "minor nuisance". https://www.cdc.gov/hiv/basics/statistics.html
People who don't have access to truvada definitely aren't going to be getting cutting-edge gene therapy any time soon. And how many people died of type I diabetes in 2015?
Re: CRISPR eliminates HIV-1 infection in live animals
#114Earlier quoted context omitted.
Are there other nations which have less demanding requirements, but still decent vetting? Why can't these kinds of ideas go there?
One factor is that by far the biggest profits are to be had in the US. Maybe you can get approved in Australia or Sweden, but that will pay negligible sums compared to getting into the US market.
Re: CRISPR eliminates HIV-1 infection in live animals
#115Earlier quoted context omitted.
So, was he right?
Short answer: Yes. Longer answer: When I first read it, I didn't think that the limitation that he had proposed applied to the type of device that we were making. He was really criticizing a similar but-not-identical type of fusion concept, and I clung to the differences. However, as our work progressed, I saw that the basic concept applied, which is that the scattering which would occur in a plasma (or a beam) would…
Re: CRISPR eliminates HIV-1 infection in live animals
#116In 2013 a very highly-placed Goldman Sachs exec, a friend of a friend, told me his AMFAR contacts predicted a 'genetics-based cure' in a 3-4 years instead of the 10 years they publicly projected. The rationale was donations would stop if people knew how close they were to a cure.
Re: CRISPR eliminates HIV-1 infection in live animals
#117In 2013 a very highly-placed Goldman Sachs exec, a friend of a friend, told me his AMFAR contacts predicted a 'genetics-based cure' in a 3-4 years instead of the 10 years they publicly projected. The rationale was donations would stop if people knew how close they were to a cure.
Even if AIDS is defeated, there's always other medical maladies that affect people. MRSA, for one.
Re: CRISPR eliminates HIV-1 infection in live animals
#118Earlier quoted context omitted.
Given billionaires running their own space programs it makes me wonder why there aren't more billionaires running biologic research companies. Between life extension and immunity to (or protection from) really pathological conditions it seems like their interests would be aligned with folks like this.
> billionaires running biologic research companies D. E. Shaw Research is exactly this. Haven't heard of others, though.
Re: CRISPR eliminates HIV-1 infection in live animals
#119Back in 2011, there was an announcement from MIT about a new approach to a broad-spectrum antiviral that appeared to work.[1] This goes way beyond an AIDS-specific cure. But it was at MIT Lincoln Labs, which doesn't usually do bio. So the researcher moved to Draper Labs, but didn't get much funding. Then that funding ran out. Now the guy behind this is trying to get funding on Indiegogo.[3] The problem seems to be th…
Given billionaires running their own space programs it makes me wonder why there aren't more billionaires running biologic research companies. Between life extension and immunity to (or protection from) really pathological conditions it seems like their interests would be aligned with folks like this.
Re: CRISPR eliminates HIV-1 infection in live animals
#120Earlier quoted context omitted.
My scientist friends tell me China is paying well, making funding available, and has a lower go-to-market burden. Innovation appears to be literally moving to China as talent is being drained away from the US & Europe.
Just for biotech?