In my experience, the developers who fall into this trap of despair almost always do so because they aren't consciously choosing what tools to use; instead they are letting the tools choose them. They see job descriptions demanding AngularJS or ReactJS and they think that they must learn it, or someone posts an article here and they don't want to feel left behind. Choose a library or tool because it improves your dev…
So what do you do about jobs asking for Angular/React experience? Just tell them you have none because you haven't needed to use them yet? Or avoid those jobs? (There are a lot)
The learning curve for React is pretty smooth, so I'd mostly check if they had experience of building the types of apps we were doing with other approaches - and whether they'd seen any ill effects from those choices.