I think I could have written this article a few months ago, when I was a huge Python fan and would spend a significant amount of time telling my friends in academia to stop using Matlab and start using Python. Then I started working in a research lab myself, and I haven't used Python since. Very simply, there's an immense amount of code written for Matlab that I can learn from in domain-specific instances, hardware v…
Having said that, I had a similar situation at my research lab and have now almost replaced Matlab.
This process was mostly organic, starting with me changing my personal post-processing workflow when I switched to IPython Notebook as a logbook and plotting library (i still use gnuplot occasionaly).
Soon I started having to port bits of Matlab and C code to Python and Cython to allow me to continue using the logbook, and I found I was becoming a lot faster at creating new modules and tools, mainly because the programming component was now intricately linked to my workflow (and more fun)
The tipping point was when I converted a notebook into a slideshow for a presentation I had to do for the group. Everybody was more interested in how I made the presentation then in my results, and wanted access to the new tools. I provided them with the git repo (and git tutorial), gave people notebooks I had written to log coding practices and demos of my code (I have poor memory) and encouraged people to contribute back.
Getting people to contribute back is still the hardwork: Everyone is shy to share their code, but the Professors starting preferring IPython Notebooks. New code is now usually written in Python first, and sometimes ported to Matlab and even the hardcore Matlab researchers are starting to show interest because of the speed and flexibility of the new code.
Basically, I found Matlab is definitely replaceable - and can only improve workflow (speed it up if nothing else). There are a few instances when specific hardware requires Win driver access through a Matlab plugin, but there are ways to interface with these too.