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Sleep research led to a new sleep apnea drug

temertymedicine.utoronto.ca

101–110 of 161 posts

Re: Sleep research led to a new sleep apnea drug

#103

I wake up without my cpap mask after a few hours every night. In total I might get 6 hours with it after putting it on multiple times. Doctors think I’m doing fine due to total amount of hours used, and my resmed cpap claims I’m at below 1 event/hour. I’m not doing fine and I think the numbers are lying to me. I snore a million, my mouth gets dry, and my nose tightens up, so my nasal mask isn’t always that nice to us…

Keep at it - there are a ton of things you can try which will help. Try to use reddit to see what other people are looking at.

If there is one thing I can recommend you - get the Wellue O2 Monitor. This wil montior your O2 saturation through the night - if the saturation is dropping, you know that there is an issue, irrespective of what the resmed cpap claims. The resmed cpap figures cant be trusted imo.

But once you know what the saturation levels are, you can try a LOT of things which might help. Different cpap masks, head of bed elevation, mouth tape, neck straps - what you end up using will depend on your condition. But imo - dont rely on doctors to diagnose and fix you - you will have to do it yourself. Fortunatately there is a ton of people who are trying things out in reddit and extremely unlikely that you have a conditoin which is not fixable.

Just keep at it and track it using the O2 ring and try out what works for you.

Re: Sleep research led to a new sleep apnea drug

#104

I went through the whole process of seeing an ENT, using the machine for the at-home sleep study so insurance would give me a CPAP, then not being able to sleep with a CPAP, and over the course of a couple years I fixed my sleep apnea by fixing my posture and breathing. If you have forward head posture or are not used to breathing through your nose, you might also benefit from this. I think it’s kind of crazy that we…

Thank you for this, I will definitely try it today! What is your opinion on Wim Hof breathing exercises, are they helpful in a similar way? I am asking because I do them occasionally and feel great every time.

Re: Sleep research led to a new sleep apnea drug

#106

For me the CPAP was too damn invasive. Fail. So as an alternative they made me a dental appliance. I put it in at bedtime and it kept my lower jaw jutted out just enough to maintain airflow. It worked :)

Yes! I had a mandibular advancement device for many years, but after about 10, my lower jaw stopped resetting all the way in the morning. I forced myself to find the right CPAP (nasal pillows with fabric elastic chin strap to keep my mouth closed). It's been about 5 years and my jaw finally is >95% back to normal (YMMV).

But by far the most critical part of getting CPAP to work was using an open source program to review the SD card raw data every morning, learning the interplay between max/min pressure, temperature, humidity, and ramp. Gaining access to the admin controls on my AirSense and fiddling it myself over weeks to find the right settings--this was the only way I made it work. The idea of waiting 6 months to make a change to the pressure was bonkers to me. Especially, for some reason, my brain is shit the next morning if I over oxygenate with too high max pressure overnight, worse than not wearing it at all!

But once you dial in the settings. It's magic.

Re: Sleep research led to a new sleep apnea drug

#107
post #2

People should be more aware of the symptoms of sleep apneas - the lack of energy during the day, feeling tired, waking up throughout the night, waking up tired/exhausted, etc. People with untreated sleep apnea have multiple folds higher chances to be depressed, unemployed, and have trouble with basic life functions, in addition to the long term health consequences of depriving your brain from Oxygen. I've suggested 4…

Would you had precise kits references to share? It is quite hard to figure out what has cheap electronic versus what works. Thanks!

Re: Sleep research led to a new sleep apnea drug

#108
post #2

People should be more aware of the symptoms of sleep apneas - the lack of energy during the day, feeling tired, waking up throughout the night, waking up tired/exhausted, etc. People with untreated sleep apnea have multiple folds higher chances to be depressed, unemployed, and have trouble with basic life functions, in addition to the long term health consequences of depriving your brain from Oxygen. I've suggested 4…

This is worth pursuing for anyone with the symptoms. However please do it with a reputable doctor, preferably associated with an established institution. Watch out for some of the specialty clinics and independent practice doctors who treat apnea like a cash cow. Sleep study scoring is theoretically set by strict rules, but in practice there can be differences between operators and clinics. Some clinics use this to t…

Get 2 opinions. And yes about weight - some people won’t have Apnea if they get their BMI to like 25 or whatever.

Saying that I have a CPAP machine and love it.

Re: Sleep research led to a new sleep apnea drug

#109
post #87

Earlier quoted context omitted.

Three more things to try if you haven’t, on a “can’t hurt” basis: nightly Avamys spray (might need a scrip depending on where you are), magnesium glycinate before bed, little bits of plastic that go inside the nostril and hold them open.

Also worth a try... B1 (thiamine) seems to help for me. I don't have objective numbers, but I disturb my spouse with my snoring and breathing troubles far less. I believe I have (undiagnosed) central sleep apnea rathee than OSA though, it's been a long time since I had a sleep study, but I had only one event over a few recorded nights... But some nights it's pretty bad.

Thanks, ordered some, will give it a shot

Re: Sleep research led to a new sleep apnea drug

#110
post #2

People should be more aware of the symptoms of sleep apneas - the lack of energy during the day, feeling tired, waking up throughout the night, waking up tired/exhausted, etc. People with untreated sleep apnea have multiple folds higher chances to be depressed, unemployed, and have trouble with basic life functions, in addition to the long term health consequences of depriving your brain from Oxygen. I've suggested 4…

I've tried a CPAP machine for 6 weeks and felt no different and gave up. I think I was a 6 on the scale. I wish it had worked though! Currently I've just given up and embracing feeling relatively tired all the time. I've tried side sleeping devices (woody knows backpack) mandibular advancement splints etc. So hard to tell (I find anyway) to get to a definitive answer

If you truly have sleep apnea it’s not just about feeling refreshed. There could be other reasons you’re tired.

But sleep apnea is really bad for your heart and lungs and does damage to them over time.

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