Earlier quoted context omitted.
... Back and forth, forever?
)) ((
Wild to see multiple references in one place! That was one of the more memorable scenes ever…
Fecal transplants for autism deliver success in clinical trials (2019)
101–110 of 250 posts
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#102Earlier quoted context omitted.
Well no, what they're saying is it seems to be capable of reducing autism-related struggles and misbehavior, not that it can somehow remove autism. Truly removing autism in any meaningful way is probably impossible since the brain was trained with it since birth.
No, that appears to be the implication of this study, which frankly seems like such a large effect that I'm pretty skeptical! I'd say "where's the control group" except the claimed effect is so large that you kind of don't need one, if it's real: > Prior to the study, 83% of participants had "severe" autism. Two years later, only 17% were rated as severe, 39% as mild or moderate, and incredibly, 44% were below the cu…
My reasing of the study is children with significant gut issues and diagnosed with autism see a significant reduction in symptoms when the gut issues are treated.
Which leads me to wonder if for some of these children is the root cause just gut issues.
If all they have figured out how to so is treat significant gut issues that sounds very promising.
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#103I got bad chronic constipation after four years as a strict carnivore. I didn't get relief just by adding back fiber, but I did by adding fermented foods like kimchi. I wonder if ferments are a more natural way than fecal transplants to repair the gut microbiome, possibly treating autism. Studies have been non conclusive, but this story makes me think it's worth pursuing.
Why did you follow a strict carnivore diet? Health? Accident? Aside from the constipation did it benefit your health?
Dieting is calories in and calories out, but protein takes more calories to digest than fat or carbs and is often very filling so it's a good way to help someone diet who struggles with feeling hungry.
You feel satiated and you're reducing your caloric intake. You can only eat so much beef jerky compared to eating a whole bag of chips before getting sick. It's helpful for people who are binge eaters.
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#104Earlier quoted context omitted.
I'm guessing that the kids now have less stomachpain, constipation, and are feeling less bloated/nauseous. Thus have less voilent reactions
That's what I'm saying. It's a misdiagnosis. Whether or not they have tantrums should not be a factor in whether or not they are high-functioning or low-functioning.
"High-functioning" and "low-functioning" are not meaningful as permanent diagnoses, because how a person functions is heavily-dependent on their environment (social, physical, and societal), including stimulus and chemical signalling from their own body.
An environment in which one person can thrive, labour, and enjoy life could be boring or incomprehensible or unduly stressful to another. I know people who would be diagnosed "low-functioning" if assessed in an everyday environment, but "high-functioning" if assessed in a clinical environment, and I know people who might not be diagnosed at all in an everyday environment but would be diagnosed with several seconds of acronyms in a clinical environment; and I know people who've been able to fight to get themselves an everyday environment that works for them, and I know people with vast potential who have conceded that fight and are rotting in the social care system.
If you eliminate what "should not be a factor" from the diagnostic process, then you eliminate the high-functioning / low-functioning distinction entirely. But all models are wrong, and some models are useful: while I find this particular model distasteful, there are contexts where it is necessary to get people in an environment where they can thrive (which, for children, usually means getting their parents the support they need, and occasionally the education).
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#105>> In early 2022 Krajmalnik-Brown and colleagues patented a specific bacterial formulation and spun-off a commercial company called Gut-Brain Axis Therapeutics. I was a little surprised to see this. So the university researchers use time and money from the university to make a discovery, extending on previous published research, and then patent it and start their own for-profit? Excuse my ignorance, but is that how i…
Yes this is very common and a big part of why scientific progress often seems so hamstrung
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#106Absolutely outrageous/hilarious clickbait title. It's not for autism but totally opposite.
Did you also think "treatment for cancer" caused cancer where there was none?
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#107First they gave them the name "assburgers" (aspergers) and now this is the solution medicine is proposing?
It's like the medical community wants all high functioning autistics to get bullied like hell in their formative years. Similar irony to "lisp" being unpronounceable by the very people who have a lisp.
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#108> Prior to the study, 83% of participants had "severe" autism. Two years later, only 17% were rated as severe, 39% as mild or moderate, and incredibly, 44% were below the cut-off for mild ASD.
Pretty incredible if true!
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#109>> In early 2022 Krajmalnik-Brown and colleagues patented a specific bacterial formulation and spun-off a commercial company called Gut-Brain Axis Therapeutics. I was a little surprised to see this. So the university researchers use time and money from the university to make a discovery, extending on previous published research, and then patent it and start their own for-profit? Excuse my ignorance, but is that how i…
It's quite common historically. The Entrepreneurial State by Mariana Mazzucato looks at this phenomenon of companies privatizing the benefits of publicly funded research and, she argues, not giving enough in return
The economist Mariana Mazzucato has some eye opening books about innovation and the role of governments. They are eye opening and dispel a lot of myths
Re: Fecal transplants for autism deliver success in clinical trials (2019)
#110Many autistic children have extremely limited diets. For example, a geneticist friend of mine saw a case where an autistic child had been referred for genetic testing because of horrific, chronic, spontaneous wounds on gums and skin. Turned out to be scurvy, because he had exclusively eaten Wheat Thins for the last 3-4 years, which aren’t fortified with vitamin C. I would fully expect that a monotonous diet leads to…
Imagine the factor overlooked is the nasty but nutritional hospital food they got when receiving the transplant (assuming they got hospitalized).
Doesn't seem like something that would require an inpatient stay.