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MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

sciencedaily.com

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Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#101

Post by catigula »

cluckindan wrote: post #79
catigula wrote: post #34

These psychedelic treatments always have substantial limitations, and this is no different; 1. Low volume cohort i.e. 40 participants per dose group 2. Industry sponsored study i.e. MindMed. 3. Think about it; how do you blind psychedelics? It's pretty obvious you're on one when you take it.

Let me guess: Those limitations are ”unscientific” in this context, but when the article is about the dangers of cannabis, they are suddenly okay?

This isn't unscientific per se, it's just low quality science. No conclusions should be drawn. There are known treatments with extremely robust, good science.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#102

Post by IAmBroom »

OutOfHere wrote: post #13

Of course they want to repackage a cheaply synthesized substance at 100-1000x the costs even though the original likely works just as well. That's pharma for you.

You are fabricating "facts" so you can diss the experimenters.

So cool. So edgey.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#103

Post by IAmBroom »

aswegs8 wrote: post #40
Rygian wrote: post #4

The "surprising way" is by using a derivate of LSD. I'd argue that the surprise is rather on this: "In clinical trials, a single dose significantly outperformed standard treatments, offering hope to those who have found little relief elsewhere."

It is no derivate. It's just the tartrate salt of LSD. There is no pharmacological difference. It's like saying I got this new Magnesium Tartrate which is now different to the Magnesium Oxide / Citrate / Glycinate / whatever you are taking. It might affect stability or absorption rate or similar, but Tartrate itself doesn't have an effect.

> It is no derivate. It's just the tartrate salt of LSD.

I think you're unclear on the meaning of "derivate".

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#104

Post by jMyles »

simulator5g wrote: post #83

This will be like legal weed. Assuming it isn't already, the pharma bean counters will turn it into something awful.

...legal weed is awful?

Weed is better, cheaper, safer, and more diverse that it has been in my lifetime (and I happily smoked it while it was illegal also).

Legal weed has been an enormous success (not that there was ever much doubt that it was going to be).

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#105

Post by AndrewKemendo »

jMyles wrote: post #104
simulator5g wrote: post #83

This will be like legal weed. Assuming it isn't already, the pharma bean counters will turn it into something awful.

...legal weed is awful? Weed is better, cheaper, safer, and more diverse that it has been in my lifetime (and I happily smoked it while it was illegal also). Legal weed has been an enormous success (not that there was ever much doubt that it was going to be).

Agreed I’m not sure what the op is suggesting. I probably smoked brick weed a few times in high school but then didn’t again for ~20 years when I held a clearance.

Your local closet grower isn’t giving you a terpene percentage breakdown and guarantee of no laces or a return policy

This is actual medicine, not hobby baking or ceramics

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#106

Post by AbstractH24 »

steve-atx-7600 wrote: post #25

I’d be afraid of a treatment like this where you’re sort of different after one treatment. From experience taking ssris, I took one one that worked so well that I had to stop taking it because it removed stress to the extent that I wouldn’t get to class on time or get my homework done before deadlines. Eventually I found a medicine that worked for me. But, if there’s a “before” vs “after” one shot treatment, you have…

People underestimate the long-term impact of pharmacological treatments.

But also I get what you mean, even if its not totally rational.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#107

Post by dopesoap »

Just from personal experience I met a bunch of people who did to many psychedelics and became ego maniacs . I also had my first panic attack on acid. Also read about weird therapists taking advantage of people on psychedelics during therapy. I'm a believer in the use of psychedelic therapy but there really needs to be good protocols in place to protect patients who are very vulnerable. I really wish I could go back in time and see the Czech psychedelic clinic it sounded really cool.

Re: MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025)

#108

Post by aswegs8 »

IAmBroom wrote: post #103
aswegs8 wrote: post #40

Earlier quoted context omitted.

It is no derivate. It's just the tartrate salt of LSD. There is no pharmacological difference. It's like saying I got this new Magnesium Tartrate which is now different to the Magnesium Oxide / Citrate / Glycinate / whatever you are taking. It might affect stability or absorption rate or similar, but Tartrate itself doesn't have an effect.

> It is no derivate. It's just the tartrate salt of LSD. I think you're unclear on the meaning of "derivate".

My bad, in my language its derivate. It's equivalent to the English derivative:

"In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction, or that can be imagined to arise from another compound, if one atom or group of atoms is replaced with another atom or group of atoms."

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