101–110 of 481 posts
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I hope not, I'd rather have fewer narcissistic sociopaths in the world. He only cares about himself and what people think of him. Nothing he does is to benefit other people. He's not Iron Man, he's Lex Luthor. I guess people have always idolized the creeps of the world, though.
It will never cease to amaze me how some people think they can know somebody the've never met as well as you think you do. I attribute it to projection.
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Why would you not go first? If you are blind it cannot be worse (well it can, but there are always risks). My wife went through semi-expetimental therapy (at that time) for her MS. It was tough but ultimately a net benefit. It all depends on what is at stake - I would consider Ozempic for some weight loss but prefer, for now , go for no sugar and moderate portions. This is not life changing for me so I indeed prefer…
That's funny because Ozempic can blind you.
If you're just using it for weight loss and aren't diabetic, you have no increase in risk.
This is also why your weight loss should be monitored by a doctor.
I'll let other blind people go first, but I'm definitely some one that would love, love, love to be able to see. Driving, knowing body language, playing any and every video game out there, shoot yeah!
Why would you not go first? If you are blind it cannot be worse (well it can, but there are always risks). My wife went through semi-expetimental therapy (at that time) for her MS. It was tough but ultimately a net benefit. It all depends on what is at stake - I would consider Ozempic for some weight loss but prefer, for now , go for no sugar and moderate portions. This is not life changing for me so I indeed prefer…
My son has cerebral palsy, doesn't talk and has poor motor skills. I certainly hope this technology progresses.
Neuralink is currently running trials on quadriplegia - with people who have their motor cortex intact, but their spinal cords damaged. Cerebral palsy often involves damage to motor cortex. So wiring the implants into it might be of limited use. No one knows if it'll work, or how well.
Targeting premotor cortex? It's extremely promising, but no one knows how to do that yet. In medicine, that means "years, if not decades, of research and development", sadly.
There is a great podcast with the entire team + Noland on yt. It is ~ 8h long, but IMO it's worth the time. You get to hear things from the perspective of the chief brain surgeon, hardware team, software team, and of course Noland himself. I really recommend it, to get a better understanding of what's possible, what they had to do to get there, and how impactful this kind of research is for people with terrible condi…
Still the same depraved head of neurosurgery, Dr. Matthew MacDougall, who said: "If tomorrow laws were changed and the FDA said okay you can do some of this early experimentation in willing human participants that would be a very interesting option I think there would be a lot of people that would step up." [1] That is basically the textbook definition of unethical medical practice, so unquestionably far over the lin…
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Not trying to be snarky, but doesn't this mental model effectively allow you to ignore any/all things otherwise intelligent people have to say, simply because you disagree? If I met Einstein, and he had opinions about how to cook chicken that differed from mine, I wouldn't leap to "he's a complete moron in the kitchen!", i'd be inclined to really attempt to understand the difference of opinion. I'm not disagreeing th…
"anyone who can think critically leans towards the Democratic party" isn't something anyone who's actually intelligent would ever say.
There used to be less of that on HN, my theory is younger accounts that are more politically extreme/lefty are now here as the younger generation graduates school and posts more on HN.
There's some historical irony too since communism came out of highly educated academic elites and is responsible for an enormous amount of death and value destruction. Ideological driven academics that think they're better than everyone are particularly good at crafting insane ideologies someone outside of that insular community would not, then leveraging institutional and cultural power to force it on everyone else. The woke and gender ideologies share similar origins, same for DEI.
It's a political and ideological monoculture and it's a dangerous mixture of incredibly confidently smug and wrong.
Worth picking up Peter Thiel's first book which goes into this in some detail (he wrote it pretty young, observing the early start of this when he was at Stanford). It's wildly prescient and was from the mid 90s iirc.
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My brother has had YOPD since his late 20s. He got DBS done about 3 years ago, and it was life changing. Not only in the symptom reduction (tremors and rigidity significantly reduced -- he walked straight for the first time in years, could button his shirts again, etc), but also in lifestyle improvements around the amount and frequency of medication, the ability to sleep properly (several side effects of both PD and…
My daughter has DBS for severe Tourette's. Her quality of life before the implant was horrible -- frequent 110 dB+ screams and self-injury. The implant has reduced her tic frequency and intensity by easily 95%. It's not only given her her life back but also the lives of her family members. The potential of brain interface technology is truly incredible -- both for good and ill.
There is a great podcast with the entire team + Noland on yt. It is ~ 8h long, but IMO it's worth the time. You get to hear things from the perspective of the chief brain surgeon, hardware team, software team, and of course Noland himself. I really recommend it, to get a better understanding of what's possible, what they had to do to get there, and how impactful this kind of research is for people with terrible condi…
Still the same depraved head of neurosurgery, Dr. Matthew MacDougall, who said: "If tomorrow laws were changed and the FDA said okay you can do some of this early experimentation in willing human participants that would be a very interesting option I think there would be a lot of people that would step up." [1] That is basically the textbook definition of unethical medical practice, so unquestionably far over the lin…
This is aside from the harm it does to the rest of us to prevent experimentation by willing participants, such as barring human challenge trials to quickly test Covid vaccines.