Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Continuous glucose monitors reveal variable glucose responses to the same meals

examine.com

Post reply on HN
Print view View original

101–110 of 130 posts

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#101

Post by apwell23 »

pedalpete wrote: post #81

Blood glucose is dependent on more variables than just what you eat. Decreased sleep slow-wave activity (not just sleep time, but the actual restorative function of sleep) significantly decreases next day insulin response [1]. This is my area (I work in neurotech/sleeptech), but other things that come to mind are changes in changes in gut biome, which can be altered by previous meals, and I assume is always in flux (…

i think oura ring wanted to combine cgm and sleep values. Not sure if they ever went ahead with cgm partnership.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#102

Post by apwell23 »

sinuhe69 wrote: post #93
pedalpete wrote: post #81

Blood glucose is dependent on more variables than just what you eat. Decreased sleep slow-wave activity (not just sleep time, but the actual restorative function of sleep) significantly decreases next day insulin response [1]. This is my area (I work in neurotech/sleeptech), but other things that come to mind are changes in changes in gut biome, which can be altered by previous meals, and I assume is always in flux (…

What about the famous breakfast? One prevalent theory among nutritionists is that the breakfast has huge influence on the insulin responses during the day: a low carb/no sugar, high protein and fat breakfast will not spike your blood glucose level and therefore will lead to a more moderate response to meal intake during the day as opposite to a high carb breakfast. I think the study should control this variable as we…

> One prevalent theory among nutritionists

why don't they test it. should be easy create a study?

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#103

Post by lrhegeba »

UomoNeroNero wrote: post #78
nomel wrote: post #67

Earlier quoted context omitted.

Do you see any relation to physical exertion of the day before/after? What about mental signals, like "I'm going to be walking a bunch tomorrow"?

I am a developer and i work from home. In my experiment i ruled out “any kind of movement” :-D (no, i am not a bag of fat, only a lotto e “not in perfect shape”). But. I can confirm that lot of stress and lot of coffe have a big and misurable effect.

thanks for "misurable". i'll steal this wonderful combination of miserable and measurable, i see lots of use in devops for it... ;-)

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#104

Post by jeffybefffy519 »

cyberax wrote: post #84
jeffybefffy519 wrote: post #74

Earlier quoted context omitted.

If you think about it, Evidence Based Medicine is very much against Medicine 3.0 whereby individualized treatments/therapies are used.

Why?

Because evidence based medicine is often about broader problems, medicine 3.0 is about solving problems for a specific person. It could be a rare type of cancer that a specific treatment has been crafted for that person - in this case theres no evidence to say that exact treatment works, maybe the over arching therapy is backed by evidence but it feels like a trend away from needing strong evidence to back the application of the therapy.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#105

Post by ddorian43 »

GuinansEyebrows wrote: post #53
ddorian43 wrote: post #14

Earlier quoted context omitted.

How about just not eat carbs at all and have more consistent & lower blood sugar? (this was an interesting case https://www.youtube.com/watch?v=CG8UU7P8FBU ) I do keto diet long term but for other reasons, often the epilepsy version where it's more strict and higher fat.

every endocrinologist i've ever had says you need at least some carbohydrates. that said, they're usually not nutritionists, and there's historically been so little focus on food as medicine within western medicine that i think we "officially" know as much about that as we do about diabetes at all (which is a lot, but still surprisingly little). there are plenty of good reasons we eat carbs (especially complex carbs,…

> not eating cake sucks more than having to plan to eat cake :)

But you have never felt the alternative. It's not just eating cake. You have to see the whole video that I linked to understand the differences (they might not all apply). Think a smoker who've never known what's it like without smoking.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#106

Post by ddorian43 »

broost3r wrote: post #75
ddorian43 wrote: post #14

Earlier quoted context omitted.

How about just not eat carbs at all and have more consistent & lower blood sugar? (this was an interesting case https://www.youtube.com/watch?v=CG8UU7P8FBU ) I do keto diet long term but for other reasons, often the epilepsy version where it's more strict and higher fat.

dad of an 8 y/o T1D here, and tbh, "how about just ..." is about the worst thing you can say to anyone dealing with this, especially given the subject of this post. things are just never the same. maybe they will be later in adulthood? i feel like i'm in a position to beta test this with my kiddo and i don't like it at all.

I understand that T1D is special, but this is said for every disorder.

There are many levels to keto diet, and believe me, you can't do the epilepsy version even if you'd wanted, it takes time and hard effort, for children it's done inside a hospital.

So assuming you watch everything they eat, you can keep track of GCM, and try very slowly. Like going from 60-30-10 carb-protein-fat to 50-30-20 ratio, do they have better consistent blood sugar ?

There should be protocols to do this for T1D the safest way.

Watch the video.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#107

Post by Zanni »

pedalpete wrote: post #81

Blood glucose is dependent on more variables than just what you eat. Decreased sleep slow-wave activity (not just sleep time, but the actual restorative function of sleep) significantly decreases next day insulin response [1]. This is my area (I work in neurotech/sleeptech), but other things that come to mind are changes in changes in gut biome, which can be altered by previous meals, and I assume is always in flux (…

Well, yes, but it's also pretty dependent on what you eat. From the article: "Additionally, the summarized study did not record the timing of snack and water consumption."

A carb-heavy snack before a meal is going to result in a radically different response than eating the same meal on an empty stomach. I'm glad they acknowledged it, but it feels absurd to publish with this headline if they didn't record snacks.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#108

Post by pedalpete »

apwell23 wrote: post #101
pedalpete wrote: post #81

Blood glucose is dependent on more variables than just what you eat. Decreased sleep slow-wave activity (not just sleep time, but the actual restorative function of sleep) significantly decreases next day insulin response [1]. This is my area (I work in neurotech/sleeptech), but other things that come to mind are changes in changes in gut biome, which can be altered by previous meals, and I assume is always in flux (…

i think oura ring wanted to combine cgm and sleep values. Not sure if they ever went ahead with cgm partnership.

They just announced CGM integration last week.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#109

Post by lytefm »

apwell23 wrote: post #101
pedalpete wrote: post #81

Blood glucose is dependent on more variables than just what you eat. Decreased sleep slow-wave activity (not just sleep time, but the actual restorative function of sleep) significantly decreases next day insulin response [1]. This is my area (I work in neurotech/sleeptech), but other things that come to mind are changes in changes in gut biome, which can be altered by previous meals, and I assume is always in flux (…

i think oura ring wanted to combine cgm and sleep values. Not sure if they ever went ahead with cgm partnership.

Yeah they bought veri.co last year and announced the integration of metabolic into their platform last week.

As the authors mention in the end, personalized nutrition based on CGM only makes less sense than also integrating sleep, stress, movement,... - which Oura is really good at.

Re: Continuous glucose monitors reveal variable glucose responses to the same meals

#110

Post by Jarmsy »

nomel wrote: post #67
UomoNeroNero wrote: post #66

Earlier quoted context omitted.

I’m diabetic and manage it with a CGM and insulin pump (HbA1c at 6.8 after many years of struggles). For convenience and my experiment, I eat practically the same meals at lunch every day, precisely weighed, always starting from very similar morning glucose levels, and strictly respecting timing and consistency. I NEVER get the same response. Never. It’s an experiment I’ve been running on myself for a year. It’s usef…

Do you see any relation to physical exertion of the day before/after? What about mental signals, like "I'm going to be walking a bunch tomorrow"?

I definitely see effects on my glucose the day after when I change my exercise routine, such as doing an extra LISS session. Anticipation of something stressful or exciting does also have an effect. I haven't noticed any effect from simply expecting more exercise later (without emotions attached). I believe a lot of this comes down to liver and muscle glycogen storage and release. (I'm T1)
Post reply on HN