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GLP-1 drugs: An economic disruptor? (2024)

wildfirelabs.substack.com

101–110 of 553 posts

Re: GLP-1 drugs: An economic disruptor? (2024)

#101

Is there a term for this style of writing? It's like a longform linkedin post. I don't mean this as a criticism, it just seems like written language is evolving to better capture our diminishing attention spans.

I think it can best be described as tweet storm/thread style writing.

Everything has to be distilled down to ~200 char chunks that can be understood on their own as well as within the wider context.

Re: GLP-1 drugs: An economic disruptor? (2024)

#102

Is there a term for this style of writing? It's like a longform linkedin post. I don't mean this as a criticism, it just seems like written language is evolving to better capture our diminishing attention spans.

I am a fan of Carroll Quigley's style of writing (Georgetown University professor and ole Slick-Willie's mentor). I find having DeepSeek restate articles in his style to be much more enjoyably ingestible.

Wow, I just followed your suggestion and the output text was exactly the style of writing I enjoy and try to employ myself. Gonna check Quigley out. Thank you!

Re: GLP-1 drugs: An economic disruptor? (2024)

#103

> alcohol spending fell 85% You've replaced one drug with another. Freud would be proud. > If you told someone in 1850 that air conditioning would reshape the global economy, they'd think you were crazy. This is incredibly misinformed. You've lived /with/ refrigeration and /without/ malaria for so long you have no Earthly idea how people in the opposite state lived their lives or saw the world around them. > We're di…

I can't understand this type of thinking.

"you replaced this drug with hundreds of known downsides with one that has none"

Nice nonargument for the rest of your post. It's somehow misinformed to state the fact that the southern manufacturing industry simply cannot exist before air conditioning

Frankly your attitude is evil and you are a proponent of evil.

Re: GLP-1 drugs: An economic disruptor? (2024)

#104
post #88

The article posits that 80% of the top income quintile will be on this medication. I have to ask, why? (I'm not in the US, I should add). Like, sure, is the average American overweight? Yes. Are 80% of the top 20% of earners? Seems pretty doubtful, plenty of the rich look to be in reasonable shape. That statistic suggests that 80% of successful people have such poor impulse control that they end up seriously overweig…

There are some signs that these drugs have effects beyond just apetite supression leading to weight loss. I recall reading something about them having a direct slowing effect on the metabolism, which increases longevity, among other benefits. I can foresee it being used like a supplement among those who can afford it.

Re: GLP-1 drugs: An economic disruptor? (2024)

#106

I would feel like an absolute failure if I need medicine to help create willpower. EDIT: under the assumption of an average person who is not under any medical condition that may result in lack of willpower

This is the same line of thinking as "drug addicts should just stop doing drugs."

Re: GLP-1 drugs: An economic disruptor? (2024)

#107
post #51

Is GLP-1 really changing general impulse control? But I do buy the argument. If impulse controlling drugs are going to be effective, the economic impact is basically not quantifiable... not only the economic impact but it would change society as a whole in extremely fundamental ways (e.g. dating)

So this drug would mess with my head – am I understanding it right?

Maybe gut? Lot’s of serotonin receptors there, right?

Re: GLP-1 drugs: An economic disruptor? (2024)

#108
post #30

I'm from the country of Ozempic and Wegovy and neither Novo Nordisk nor our media have been portraying these drugs as general purpose anti-addiction drugs. However there have been some international studies that reveal that it might actually be. Can Novo Nordisk extend their patent of their existing drug if they find new applications for the drug? Some of Silicon Valley's excess productivity over the rest of the worl…

Yes, a patent can be extended with a different use case. Drug repurposing or repositioning is mostly done exactly because of this financial benefit. Unfortunately that does not apply to currently generic drugs, so pharmaceutical companies don't put the resources into repurposing off-patent drugs that could be helpful.

https://en.m.wikipedia.org/wiki/Drug_repositioning

Re: GLP-1 drugs: An economic disruptor? (2024)

#109
post #86
post #56

Earlier quoted context omitted.

Because the author assumes that the drugs are not only anti-obesity drugs but impulse controlling

Correctly assumes*

But this thread and the article's comment sections have many people saying it doesn't really do that for them.

Re: GLP-1 drugs: An economic disruptor? (2024)

#110

Earlier quoted context omitted.

> Yes well your PCP / pharmacist should not have prescribed you an appetite suppressant when you have below average body fat %. Why do you think this? I agree that people who have associated risk factors should be prioritized, but if there's enough for everyone why wouldn't we give it to anyone who wants it?

People who don't need to be chronically medicated should not be. There are always side effects, and we don't even know for sure what the long term risks of these medications are yet. And crowing about saving $200/mo not buying food at Starbucks, well now Novo Nordisk is getting that. Toast a bagel at home for $0.50/day instead.

I am not an expert but my impression is semaglutide has been in development since the 90s and in use as a drug for about a decade for people with diabetes. The drug and mechanism are old, the use is new.

I do not agree that people who don't "need" to be chronically medicated should not be. I think you can decide to take whatever you want for your own reasons. I am not going to tell you what you can and and can't take - unless you're like...taking something that makes you destructive or generate externalities or whatever. But this seems like the opposite?

Lots of questions here around profit and the awful medical system in the US, but on a basic level I think people should be able to do what they prefer and is safe.

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