Twice-Yearly HIV Shot Shows 100% Effectiveness in Women

Post by RHSeeger » Tue, Dec 03, 2024, 2:40 PM UTC

n4r9 wrote: post #62

thaumasiotes wrote: post #55

Earlier quoted context omitted.

> Do you have kids, if so how do you deal with frequent disruptions to the morning routine? Do you not have days where you just need to get up and go e.g. to catch a flight, get to a meeting, take a kid to school, or because you stayed up late and got drunk, etc... and taking vitamins took a back seat? This is crazy. You deal with the morning routine by taking your pills when the alarm goes off, because there's nothi…

> there's nothing the kids can be doing that won't wait for that There are plenty of things kids - especially young kids - will do that require you to push tasks back. Like a vomit, poo, or spillage situation needing immediate attention. Or throwing a tantrum if you try to bring them back upstairs where the pills are (thus waking everyone else up). Not to mention that it can be exhausting if they're not sleeping well…

Post by m3kw9 » Tue, Dec 03, 2024, 2:52 PM UTC

bobthepanda wrote: post #9

t-writescode wrote: post #2

This is incredibly exciting! The main method available for PrEP, in the United States, at least, is a daily pill. I think (I don't know) there is a monthly shot, too. Daily pills take a lot of time investment; monthly shots are better; but once every 6 months is awesome! Especially in circumstances where it might be difficult to guarantee a daily pill or even a monthly shot.

There is a generic daily pill (Truvada), a more expensive one (Descovy) and an every two months shot (Apretude.) Apretude has lower efficacy than Descovy or Truvada, but once you factor in human error in taking a daily pill regimen, it is more even. Human error is a significant factor since the current treatment protocols say if you’re not sure whether or not to take it, it is safer to skip than to accidentally doubl…

Post by thegrimmest » Tue, Dec 03, 2024, 3:10 PM UTC

JumpCrisscross wrote: post #100

mschuster91 wrote: post #98

Earlier quoted context omitted.

The problem is, as usual, payment. There have been many failed attempts at developing suppressive, curative and preventative medicine against HIV over the decades, and not all of that was funded by charities or government grants that don't expect repayment - especially not the later stage trials.

> problem is, as usual, payment If only we had an institution with the aim of pursuing the long-term interests of the collective.

Post by JumpCrisscross » Tue, Dec 03, 2024, 3:13 PM UTC

raylad wrote: post #101

JumpCrisscross wrote: post #95

Earlier quoted context omitted.

> This treatment does not in fact prevent HIV infection. It prevents infected cells from producing viable virus particles Lenacapavir interferes "with multiple essential steps of the viral lifecycle, including capsid-mediated nuclear uptake of HIV-1 proviral DNA (by blocking nuclear import proteins binding to capsid), virus assembly and release (by interfering with Gag/Gag-Pol functioning, reducing production of caps…

The references you provided are prescribing information and to other drugs which actually are anti-retroviral. You did not provide any reference showing that cells that are actually infected but inhibited from producing virus through late stage assembly inhibitors are effectively eliminated by the immune system.

Post by alecco » Tue, Dec 03, 2024, 3:16 PM UTC