Maybe I'm a cynic but it strains credulity that the miracle cure is also a laundry list of fad health trends from the the last decade. Gluten free, intermittent fasting, yoga, melatonin, probiotics, etc etc
Just wait for another paper claiming that the ketogenic diet is what really works.
Reversal of cognitive decline: A novel therapeutic program
101–109 of 109 posts
Re: Reversal of cognitive decline: A novel therapeutic program
#102Earlier quoted context omitted.
I think it is pretty easy to deny. The CDC breaks out obesity by demographics[1]. White adults have an obesity rate of ~29%. This is the same as other predominantly white/Anglo countries like Canada, Australia, and the United Kingdom[2]. Maybe 29% is staggeringly unhealthy, but it isn't American culture to be that overweight. Being overweight is fairly widespread and not unique to America. Probably it has more to do…
> it isn't American culture to be that overweight > hispanics and blacks are considerably more overweight than whites Are these people not American?
Re: Reversal of cognitive decline: A novel therapeutic program
#103Lots of comments dismissing this out of hand because of lack of evidence, but there aren’t any conventional treatments that are very helpful for Alzheimer’s. The lifestyle adjustments suggested in the protocol are largely healthy, not that hard to do, and offer other health benefits. They are also relatively uncommon so it’s not impossible that a broad based adoption of specific habits along with testing for mycotoxi…
> Lots of comments dismissing this out of hand because of lack of evidence, but there aren’t any conventional treatments that are very helpful for Alzheimer’s. These are harmless until they become harmful. What if we develop a good cure for Alzheimer's in 10 years, this method gets debunked but the method makes many refuse to use the conventional treatment? That isn't a made up scenario, it happens all the time. Anno…
Scientific progress has often been speculative and messy. The few thousand people with ApoE4 genes who read his book and then actually commit to time-restricted feeding, exercising 4 times a week, sleeping 8 hours, and semi-ketogenic diets might have better outcomes a decade from now than those who don't. If that discourages another few tens of thousands of people from taking a potential blockbuster drug in the early years after its release, fine. It's worth the natural experiment to find out because millions of people are not getting much relief from current treatments [2]. This is even more true given that Alzheimer's isn't communicable.
[0] https://en.wikipedia.org/wiki/Ignaz_Semmelweis
[1] Which is lately experiencing a renaissance see https://charliefoundation.org
[2] Official bodies also continue to approve therapies with evidence that appears inconclusive with a higher degree of certainty than Bredeson's protocol. https://hub.jhu.edu/2021/06/21/fda-aduhelm-approval/
Re: Reversal of cognitive decline: A novel therapeutic program
#104Earlier quoted context omitted.
I don't see how that sentiment can be read into what I wrote. I looked at three racial groups in America and observed they had different obesity rates. In abstract terms - "You think this quality is specific to the whole. If you divide the whole into three parts you can see the quality differs between the parts. This implies the quality is not specific to the whole." To take that claim and infer that I mean to sugges…
There were 3 different responses that read your post similarly, as though the higher levels of obesity among Hispanic and Black people are unrelated to American culture, as though it doesn't matter what the rates of obesity are among people who aren't White. I suppose the reason why some bristle at your partitioning of American obesity rates into racial groups is that it's unclear that it's particularly relevant. Obe…
The reason to use racial groups in my example, is first because I happened to know obesity differed between the groups, and second because it offers the opportunity to look at similar groups in different countries. This example shows that there is variance within the country and similarity beyond it, which I think makes a good case that the culture of the country is not what's responsible.
Regarding your point on violence, suppose it were the case that left handed people had a murder rate 100x higher than right handed people. Now, imagine too that the OECD countries, or whichever group you would like to compare America too, were 99% right handed and America were only 90% right handed.
Would it make sense in this case to say that American culture was the root of the problem with American violence if right and left handed Americans committed violence at the same right as their OECD counterparts? I wouldn't think so. I would think the explanation would be as simple as "greater proportion of more violent left handers".
I realize in the violence example that I've simplified and exaggerated the case compared to obesity. I am not claiming that obesity rates are similar to my example.
Re: Reversal of cognitive decline: A novel therapeutic program
#105Re: Reversal of cognitive decline: A novel therapeutic program
#106Earlier quoted context omitted.
México, Costa Rica, Korea, and Greece would like a word, on both working harder and eating better: https://www.weforum.org/agenda/2018/01/the-countries-where-p...
Mexico is more overweight than the US and tops your list of reported working hours.
In fact, the only other country with a population of more than 200,000 people with a higher obesity rate than the US is Kuwait.
Re: Reversal of cognitive decline: A novel therapeutic program
#107Re: Reversal of cognitive decline: A novel therapeutic program
#108tldr personalized techniques: - Optimize diet: minimize simple CHO, minimize inflammation. - Patients given choice of several low glycemic, low inflammatory, low grain diets. - Enhance autophagy, ketogenesis - Fast 12 hr each night, including 3 hr prior to bedtime. - Reduce stress - Personalized—yoga or meditation or music, etc. - Optimize sleep - 8 hr sleep per night; melatonin 0.5mg po qhs; Trp 500mg po 3x/wk if aw…
Can we get one supplement pill that merges all of those that need to be consumed? Kthx.
Some exceptions apply: Sprinkle flax seeds on top for omega 3s, use iodized salt for iodine (seaweed is high in iodine but also high in bad heavy metals), get fresh air and sunshine for vitamin D, pick out your favorite source of vitamin b12. I believe you'll still need potassium.
For exercise: A good place to start is to walk and bike for transportation. Read this book if you're wanting to be convinced that exercise is a magic pill: Spark: The Revolutionary New Science of Exercise and the Brain
Re: Reversal of cognitive decline: A novel therapeutic program
#109Earlier quoted context omitted.
Can we get one supplement pill that merges all of those that need to be consumed? Kthx.
Eat a can of beans and an entire bunch of bitter greens every day. That covers most of your vitamins and minerals. Some exceptions apply: Sprinkle flax seeds on top for omega 3s, use iodized salt for iodine (seaweed is high in iodine but also high in bad heavy metals), get fresh air and sunshine for vitamin D, pick out your favorite source of vitamin b12. I believe you'll still need potassium. For exercise: A good pl…