101–110 of 569 posts
I find it a bit weird that there are fewer asymptomatic cases with this vaccine? Is it somehow increasing the immune response to COVID-19?
Is this the sort of Vaccine that protects against infection or against the disease?
I don't know how many existing vaccines fall into either category here, i.e. whether there are many vaccines that prevent disease but do not even reduce the ability to spread. Would be interesting to know.
Earlier quoted context omitted.
Another huge differentiator is price. At $3 to $4, many countries will jump on board ASAP and stay away from the expensive vaccines from Pfizer and Moderna.
Maybe for less developed countries, but i think for major economies, the price difference is insignificant relative to the benefits of any vaccine.
This vaccine is cheap, 90% efficient and easy to get people vaccinated. The other ones are expensive, 95% efficient and difficult to get people vaccinated.
Is that the same vaccine that was approved in Russia? I remember Russia was working with AstraZeneca on their vaccine, but not sure if it's the same one.
Earlier quoted context omitted.
What are the storage requirements for the other two?
-80C for Pfizer, and below 0 for the other one (I forget exactly). -80C is really close to dry-ice temperatures. So I wonder if its actually -80C or if the researchers were just saying "Dry Ice".
While we now get the results from various COVID-19 vaccines I see a societal issue brewing up. How will we deal with the perceived uncertainty of the safety of these vaccines and the surrounding (dis-)infodemic? I read recently that in some European country (was it Germany?) the willingness to vaccinate against COVID-19 went down from 80% to 60%. With these numbers policy makers will have a hard time convincing the b…
Just from a software perspective: never install the big version upgrade. Usually the X.0 versions still has bugs that only come out at huge roll outs. I am inclined to wait a few months to let early adaptors test the vaccine. Medicine is a bit different though and every country probably has institutes checking the vaccines independently. A lot of eyes are on this probably. No company wants to be the company that botc…
From AstraZeneca: > One dosing regimen (n=2,741) showed vaccine efficacy of 90% when AZD1222 was given as a half dose, followed by a full dose at least one month apart, and another dosing regimen (n=8,895) showed 62% efficacy when given as two full doses at least one month apart. The combined analysis from both dosing regimens (n=11,636) resulted in an average efficacy of 70%. All results were statistically significa…
Why do they sabotaged their own messaging by using the 70% number? Reading further, it looks like the vaccine is 90% efficient. Also, "There were no hospitalised or severe cases in anyone who received the vaccine". Can we infer anything from that statement? They seem to be suggesting that the infection might be less serious in the vaccinated population...
The 70% is the combined data, so probably the most reliable estimate. For two high doses, they got 62% effectiveness and for one low and one high dose they got 90%. They don't know why the latter was more effective. 70% is still a great effectiveness rate, specially for a cheaper and easier to distribute vaccine.
With the second jab those antibodies immediately neutralize the adenovirus so it can't infect enough cells and make enough of the COVID antigens so the protection is not that strong.
The Russian vaccine avoids it by using two different strains of adenovirus for the two jabs
Title is misleading. They tested few configurations, we should use the most optimal one, not the average. Much better source: https://www.astrazeneca.com/media-centre/press-releases/2020... Good: + likely 90% effective if we use optimal dosing + no significant side effective. Looks better than Pfizer or Moderna. + already pre-produced at huge scale, 3 Bln doses in 2021 + easy to store and administer, just regular fri…
Interesting its cheaper than mRNA, i thought that was one of the benefits of using mRNA, was that it was supposed to be cheaper to manufacture.