101–110 of 266 posts
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Many are toxic (vitamin D included) in unsuitable amounts, that’s probably too strong of a statement.
The study mentions 1,000 IU D3 dosage. A quick google turns up a rough figure of 60,000 IU "daily for multiple months" can become toxic. You're probably right, most things taken at 100x the normal dose for long period of time are toxic. (Water included)
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My money is on 1. Vitamin D deficiency is caused by lack of sunlight. I'm skeptical of doctors telling me to avoid the sun and take a pill instead.
I eye-rolled at that guidance too, until a loved one was diagnosed out of the blue with stage-2 melanoma. It's terrifying. Don't screw around with sun protection. Despite what the internet says, people who work outside get it too.
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Vitamin overdoses can be serious in the worst cases. https://en.wikipedia.org/wiki/Hypervitaminosis_A https://en.wikipedia.org/wiki/Hypervitaminosis_D
While toxic amounts of basically anything are bad, introducing random facts that have no bearing on what is discussed can mislead some readers into thinking you're making a point related to the topic at hand. While it may be unintentional, this is misleading and therefore not helpful.
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Dr Rhonda Patrick was the guest if anyone is interested. Worth watching with paper and pen (or digital equivalent).
Show notes are here. https://www.foundmyfitness.com/episodes/jre-1474
00:29:32 - In the Philippines, every standard deviation increase in serum vitamin D was associated with an 8 times more likely chance to have a mild rather than severe COVID-19 outcome and a 20 times more likely chance to have a mild rather than critical outcome.
00:30:37 - In Indonesia, 98.9% of patients with vitamin D deficiency died, 88% of patients with vitamin D insufficiency died but only 4% of patients with sufficient vitamin D died.
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If you're deficient in something, your body probably up-regulates absorption. You can get higher quality vitamins with forms that are more easily absorbed, for example chelated magnesium instead of magnesium oxide. That said, I thought the evidence actually pointed to higher all cause mortality in people who take vitamins.
If you have a study that shows higher all cause mortality please link it. My hypothesis would be that healthy people don't take vitamins because they never saw the need, putting already sick people in the second category. I doubt that taking vitamins can actually do much harm in low doses.
First result: https://www.sciencedaily.com/releases/2011/10/111010173019.h...
>After adjustment, use of multivitamins, vitamin B6, folic acid, iron, magnesium, zinc and copper, were all associated with increased risk of death in the study population.
The top three links showed association between beta carotene supplementation and risk of death.
A little further down, a study showing "higher plasma concentrations of vitamin B12 were associated with a 25% increased adjusted risk of all-cause mortality per 1-SD increase" https://jamanetwork.com/journals/jamanetworkopen/fullarticle...
>The use of multivitamins overall was associated with 2.4% increased absolute risk for death (hazard ratio [HR], 1.06; 95% confidence interval, 1.02 - 1.10).
https://www.medscape.org/viewarticle/751462#:~:text=The%20us....
The conclusion I personally draw from all this is: don't take a multi vitamin. Don't take any vitamins unless I have a good reason like a tested deficiency. If I think I could benefit from a supplement then I try to increase it in my diet instead.
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The study mentions 1,000 IU D3 dosage. A quick google turns up a rough figure of 60,000 IU "daily for multiple months" can become toxic. You're probably right, most things taken at 100x the normal dose for long period of time are toxic. (Water included)
The largest dosage of D3 I can find on Amazon is 5000 IU in a 240 capsule bottle. To take 60000 IU, you'd have to take a dozen capsules daily, getting a new bottle every 20 days, probably multiple times. While possible, it does seem unlikely.
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If you're deficient in something, your body probably up-regulates absorption. You can get higher quality vitamins with forms that are more easily absorbed, for example chelated magnesium instead of magnesium oxide. That said, I thought the evidence actually pointed to higher all cause mortality in people who take vitamins.
> I thought the evidence actually pointed to higher all cause mortality in people who take vitamins. Citation absolutely needed The caveat is excessive consumption of Vitamin A (and maybe others), in some specific circumstances. Keyword: excessive
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Magnesium is something I've recently been interested in as well. Surprisingly, you don't find it in many multivitamins, or if you do, it's in small quantities. My guess is that it would make the multivitamin too large if it were included. Leafy green vegetables are a good source of Mg, but most people don't eat enough of those.
Yep, but even with green vegetables, you'll struggle to get anywhere near the daily recommendation, around 400mg per adult. And that might be significantly more if you are active in some sports for muscle recovery. Personally I can feel the difference given that I exercise daily and I do a 20000 step walks every morning. But yeah, I rely on supplements, which is kind of the easy way out. And even the very good ones a…
Also, what difference are you feeling?
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The study mentions 1,000 IU D3 dosage. A quick google turns up a rough figure of 60,000 IU "daily for multiple months" can become toxic. You're probably right, most things taken at 100x the normal dose for long period of time are toxic. (Water included)
The largest dosage of D3 I can find on Amazon is 5000 IU in a 240 capsule bottle. To take 60000 IU, you'd have to take a dozen capsules daily, getting a new bottle every 20 days, probably multiple times. While possible, it does seem unlikely.
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Turning round in a circle three times also doesn't improve your health in general. Getting the right vitamins does improve your health.
Getting too much of many vitamins can harm your health though.