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The neuroinvasive potential of SARS-CoV2

ncbi.nlm.nih.gov

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Re: The neuroinvasive potential of SARS-CoV2

#101

Post by ceejayoz »

drcode wrote: post #59
morpheuskafka wrote: post #15

Earlier quoted context omitted.

Yes, only a N95 or better mask would protect you from incoming, as opposed to outgoing, viruses, and these masks are both impractical for everyday wear and need to be conserved for public health users.

I will argue this is wrong: Only N95 or better masks have studies proving their effectiveness. I don't think we have good data on weaker masks or even "home made" masks- It's totally possible they are also effective, with proper technique. Please somebody show me data that proves otherwise, I'm totally open to it. (Note: I'm not saying I want you to post opinions from people in authority, I'm saying I want to see dat…

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373043/?fbclid...

> Quality commercial masks are not always accessible, but anecdotal evidence has showed that handmade masks of cotton gauze were protective in military barracks and in healthcare workers during the Manchurian epidemic.

> The prototype mask achieved a fit factor of 67 for 1 author with a Los Alamos National Laboratory (LANL) panel face size of 4, a common size. Although insufficient for the workplace, this mask offered substantial protection from the challenge aerosol and showed good fit with minimal leakage.

Re: The neuroinvasive potential of SARS-CoV2

#102

Post by airstrike »

aazaa wrote: post #10

From the paper: > If the neuroinvasion of SARS-CoV-2 does take a part in the development of respiratory failure in COVID-19 patients, the precaution with masks will absolutely be the most effective measure to protect against the possible entry of the virus into the CNS. It may also be expected that the symptoms of the patients infected via facal-oral or conjunctival route will be lighter than those infected intranasa…

> It may also be expected that the symptoms of the patients infected via facal-oral or conjunctival route will be lighter than those infected intranasally.

Where can I buy noseplugs?

Re: The neuroinvasive potential of SARS-CoV2

#103

Post by CraigJPerry »

allendoerfer wrote: post #88
Proziam wrote: post #63

Earlier quoted context omitted.

EDIT - Just to be clear, I'm not saying that people shouldn't take precautions or that it's not worth protecting vulnerable groups. I'm simply suggesting that perhaps there is news coverage about other things (remember the whole Hong Kong situation that we aren't hearing about suddenly?) that might still deserve some air time. The media is profiting off this story big time. It's like when the plane went missing and a…

Also is Australia still burning? A burning continent seemed important before the virus, not anymore.

Not really anymore, no

https://www.rfs.nsw.gov.au/

Re: The neuroinvasive potential of SARS-CoV2

#104

Post by hazeii »

jessriedel wrote: post #80
aazaa wrote: post #10

From the paper: > If the neuroinvasion of SARS-CoV-2 does take a part in the development of respiratory failure in COVID-19 patients, the precaution with masks will absolutely be the most effective measure to protect against the possible entry of the virus into the CNS. It may also be expected that the symptoms of the patients infected via facal-oral or conjunctival route will be lighter than those infected intranasa…

Why is it easier to get to the brain from the nose compares to the mouth or eyes?

Very possibly because the olfactory bulb is basically a bit of the brain exposed to the atmosphere. See the illustration on the wikipedia page [0].

[0] https://en.wikipedia.org/wiki/Olfactory_bulb

Re: The neuroinvasive potential of SARS-CoV2

#105

Post by pbhjpbhj »

sndean wrote: post #19
mc32 wrote: post #16

Earlier quoted context omitted.

How often would people have to replace their N95s to be of help?

It looks like CDC recommends to use them for ≤ 8 hours (continuous or intermittent) [0]. [0] https://www.cdc.gov/niosh/topics/hcwcontrols/recommendedguid...

Presumably their effectiveness is reduced then, rather than negated. Aren't they just close bound fibres that form a filter?

Re: The neuroinvasive potential of SARS-CoV2

#106

Post by ceejayoz »

tdstein wrote: post #42
bluGill wrote: post #17

Earlier quoted context omitted.

I have a small box of N95 masks in my shop - bought last summer for dust protection. When is the right time for me to put them on my family. Part of this is how long will they last before I must replace them. Or should I put them on eBay for a million dollars and hope I life to enjoy my new found wealth?

Or you could donate them to your local hospital since there is a shortage. I’m not sure they would take them, but it’s worth considering.

Local hospitals are not going to be able to take masks from some random person off the street.

Re: The neuroinvasive potential of SARS-CoV2

#108

Post by theseadroid »

clon wrote: post #61

Would this explain the apparent sudden collapse of people on the streets in China and Iran? [1] [1] https://www.snopes.com/fact-check/people-collapsing-coronavi...

In your own source it is said unproven with detailed explanation:

>If we strip the above-displayed videos of their captions, we can take a look purely at what the videos show. In one case, it looks like a person was the victim of a traffic accident. In another, it appears that a man suffered a head injury. But since these videos appeared online during heightened hysteria about an outbreak of an illness, it’s easy to see how a passerby may have made the assumption that these incidents were connected to the coronavirus.

Re: The neuroinvasive potential of SARS-CoV2

#109

Post by SketchySeaBeast »

geggam wrote: post #84
vorticalbox wrote: post #37

Question what effect is vaping having on the spread? Walking in a city in the UK I see people leave large plumes of vaper which seems to me be an excellent transport system. Warm and wet.

Score one for the cigar / tobacco smoker

As it would seem to affect smokers harder, I'd call that a draw.

Re: The neuroinvasive potential of SARS-CoV2

#110

Post by doublekill »

drcode wrote: post #59
morpheuskafka wrote: post #15

Earlier quoted context omitted.

Yes, only a N95 or better mask would protect you from incoming, as opposed to outgoing, viruses, and these masks are both impractical for everyday wear and need to be conserved for public health users.

I will argue this is wrong: Only N95 or better masks have studies proving their effectiveness. I don't think we have good data on weaker masks or even "home made" masks- It's totally possible they are also effective, with proper technique. Please somebody show me data that proves otherwise, I'm totally open to it. (Note: I'm not saying I want you to post opinions from people in authority, I'm saying I want to see dat…

No, there is a 2009 study which compares N95 mask efficiency with surgical masks, because they predict that during a pandemic N95 masks will be in shorter supply. (1)

They don't find significantly more efficiency for N95 masks, but other studies do find N95 masks slightly better. (2)

(1) https://jamanetwork.com/journals/jama/fullarticle/184819

(2) https://onlinelibrary.wiley.com/doi/full/10.1111/j.1750-2659...

Do a search on Google Scholar for "N95" in combination with "virus" or "sars" for more studies.

Really a shame that authorities, including the Surgeon General, claim that masks are not protective, despite medical science to the contrary.

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