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Increased sedentary behaviour alters metabolism and body composition (2018)

ncbi.nlm.nih.gov

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Re: Increased sedentary behaviour alters metabolism and body composition (2018)

#101

Post by ska »

SketchySeaBeast wrote: post #99
JohnJamesRambo wrote: post #91

Earlier quoted context omitted.

It's not a minor dysfunction. >Pooling data from both groups, following step reduction there was a significant decrease in whole-body insulin sensitivity (Matsuda index) (p Those are incredible p values to find in a human study.

But, as I original pointed out, it's mitigated by maintaining a non-extreme level of activity - throwing on ~10,000 steps is the difference here.

The fact that the fix is relatively easy is not really a measure of how far off things are - some pretty terrible disorders have easy fixes...

Re: Increased sedentary behaviour alters metabolism and body composition (2018)

#103

Post by outworlder »

mrzimmerman wrote: post #86
johnchristopher wrote: post #63

Earlier quoted context omitted.

What kind of sensor do you have ? I am not diabetic but I'd like to monitor my sugar level somehow.

I use the Medtronic Guardian Plus because it ties into my insulin pump which then regulates how much background insulin to give me. Dexcom, as mentioned in another comment, is a standalone sensor that doesn't tie directly into a pump. All sensors that I know of are invasive though, so they have to be replaced every 7-10 days, which requires a needle and other things to cover it. You could also just buy a glucometer (…

> I use the Medtronic Guardian Plus because it ties into my insulin pump which then regulates how much background insulin to give me.

Oh, so we are finally over that hurdle. Last time I checked there were some liability concerns that prevented manufacturers from closing the loop – the user had to input the numbers.

Re: Increased sedentary behaviour alters metabolism and body composition (2018)

#104

Post by adameast1978 »

ska wrote: post #65
adameast1978 wrote: post #47

I am all for science but I am really curious why we need studies to prove things that are this obvious and simple. Hell just with thought experiments, basic thermodynamic principles and a little Anatomy and Physiology alone you conclude most of these things.

Thought experiments based on basic principals and our still too weak understanding of bio-phys can (and have, time and time again) lead you to an awful lot of plausible but wrong conclusions. There is no real substitute for doing the science.

Really we need to do a study that says when you exercise less and sit around your body fat increases specifically in your internal organs. I think this is common sense and how fat accumulation works. This has been proven in the past and should be common knowledge. Insulin dependence related to this makes a little sense for a study but it is pretty well accepted that being obese increases your risk of type 2 diabetes. The fact that if you create a calorie deficit you will lose weight/body fat and if you don't you will increase weight/body fat is simple yet there is a diet industry built on fads and a bunch of over educated people with too many degrees in non physical science fields pushing their ideals so they can make money.

Re: Increased sedentary behaviour alters metabolism and body composition (2018)

#105

Post by [deleted] »

adameast1978 wrote: post #104
ska wrote: post #65

Earlier quoted context omitted.

Thought experiments based on basic principals and our still too weak understanding of bio-phys can (and have, time and time again) lead you to an awful lot of plausible but wrong conclusions. There is no real substitute for doing the science.

Really we need to do a study that says when you exercise less and sit around your body fat increases specifically in your internal organs. I think this is common sense and how fat accumulation works. This has been proven in the past and should be common knowledge. Insulin dependence related to this makes a little sense for a study but it is pretty well accepted that being obese increases your risk of type 2 diabetes.…

[deleted]

Re: Increased sedentary behaviour alters metabolism and body composition (2018)

#106

Post by SapporoChris »

dsaavy wrote: post #73
johnchristopher wrote: post #63

Earlier quoted context omitted.

What kind of sensor do you have ? I am not diabetic but I'd like to monitor my sugar level somehow.

The most popular ones are the Dexcom sensors and then the Freestyle Libre. Unfortunately you need a prescription for both in the US. Otherwise, if you'd like to monitor your blood sugar, you'll have to do it via a blood glucose meter and just space out your testing. You can buy those over the counter at any pharmacy/superstore and they're relatively cheap. If you end up buying a blood glucose meter, the best way to g…

If you're only mildly curious and don't wish to invest much then you might consider urine test strips. Very cheap, but the reading is also very vague also. However, they will let you know if you have a problem or not.

https://en.wikipedia.org/wiki/Urine_test_strip

Re: Increased sedentary behaviour alters metabolism and body composition (2018)

#107

Post by SketchySeaBeast »

graeme wrote: post #7
Bootwizard wrote: post #5

"Public health recommendations promoting physical activity should incorporate advice to avoid periods of sedentary behaviour." How do we interpret and apply information like this? Many people work in front a computer these days so it can't actually be applied to them (read us).

The study had people walk 10,000 fewer steps in a day. So, walking more would reverse it if the study was right. In practice it would mean taking periodic breaks to walk around a bit, and trying to arrange things such that you could walk some of your commute, or walk to the store, etc Obviously harder for people in suburbia.

Does that follow though? They took 10,000 fewer steps away, yes, but was there actually any judgement in how those steps were gained/lost? I'm curious if the same effect as those 10,0000 steps could be found simply by going out for an hour walk and still sitting for the rest.

Re: Increased sedentary behaviour alters metabolism and body composition (2018)

#108

Post by iikoolpp »

iikoolpp wrote: post #55

On one hand, my body is probably fucked from laying in bed for 18 hours a day, every single day, a year. On the other hand, moving about is exhausting and hurts so why would I want to do it? I fully plan on killing myself before 30 so it's not like I'll see the knock-on effects.

Every single reply to this has validated my decision

Re: Increased sedentary behaviour alters metabolism and body composition (2018)

#109

Post by justinator »

DoreenMichele wrote: post #95

Walking and the lymphatic system https://news.ycombinator.com/item?id=20551311 The underappreciated role of muscle in health https://news.ycombinator.com/item?id=8748147 I live without a car. I have no desire to change that fact. My condition is incurable. Running errands on foot plays a critical role in staving off deterioration that, among other things, puts me at risk for a form of diabetes.

Right on. Strength to you.

Re: Increased sedentary behaviour alters metabolism and body composition (2018)

#110

Post by mikelyons »

iikoolpp wrote: post #57
mikelyons wrote: post #56

Earlier quoted context omitted.

Why kill yourself before thirty?

I don't want to be old.

See if you can come up with some goals that will take you multiple lifetimes to achieve. Spiritual goals. Life Purpose. Just pick something and see how far you can get with it. Don't just give up, that's not why you designed all this.
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