It's also impossible for a traveling salesman to find the best route between cities, but that doesn't mean that salesmen don't travel. Approximations are often Good Enough, and there are a variety of polynomial algorithms that produce Good Enough solutions to NP problems. Everything in the real world is impossible, but we can try and get good results anyway.
A regulator trying to preempt unfair dealings with rules may have no chance, no matter how wise and disinterested, but people trying diverse strategies over time eventually settle on something that's good enough. (And some scams and business cycles are an inevitable part of that discovery process.)