Now, I realize this doesn't apply if the end game is a high dollar exit, but if you can make a decent living with your application/web site ("startup" and "founder" are overused terms in my opinion) who cares?
If you can't make a profit long term, then maybe you your idea doesn't deserve to live. Simply passing the bomb on to the next set of suckers be they the public at IPO's, or acquires, or VC investors hardly seems like the right thing to do (although no doubt it is done all the time... sometimes with incredible profits).
There is life outside the VC world. If it's a good idea and profitable and you love it....stick with it. If you are looking for a billion dollar exit... that's another thing entirely and it's time to move on to the next idea.