It is doubtless the case that Schneier is fielding constant phone calls from trade reporters asking for his opinions on the security news of the day. Taking those calls, and writing the op-ed-style pieces that generate them, is probably the bulk of his job description. And so it's to be expected that he's going to be asked questions about things like Chrome's "virus-proofness", and having given no thought to Chrome or its architecture, be at a loss for pithy commentary. Hence, "2+2=3". Thanks, Bruce.
But before you feel too much sympathy for him, remember that he always has the ability to tell the reporter, "sorry, I don't know enough to comment intelligently on this story".