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Taxi drivers rarely die of Alzheimer's

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Re: Taxi drivers rarely die of Alzheimer's

#11

Can video games provide similar benefits?

The thing about taxi drivers is that they have something at stake, while video games have no fail state effectively. You can be punished in-game, but overall it does not matter.

Also video games in general are pretty derivative, so playing the same genre probably won't help much after a certain point. But playing different ones can be very helpful, I imagine (same with other mediums).

Re: Taxi drivers rarely die of Alzheimer's

#12
> In one landmark 2000 study, neuroscientists compared the brains of licensed London taxi drivers with those of people who did not drive cabs.

Location is very important here. London cabbies have to pass The Knowledge which is an extremely difficult memory exam that only people with particular kind of brain can do.

Re: Taxi drivers rarely die of Alzheimer's

#13

> In one landmark 2000 study, neuroscientists compared the brains of licensed London taxi drivers with those of people who did not drive cabs. Location is very important here. London cabbies have to pass The Knowledge which is an extremely difficult memory exam that only people with particular kind of brain can do.

Indeed. Elsewhere in the world taxi drivers just follow the GPS.

Re: Taxi drivers rarely die of Alzheimer's

#14

> In one landmark 2000 study, neuroscientists compared the brains of licensed London taxi drivers with those of people who did not drive cabs. Location is very important here. London cabbies have to pass The Knowledge which is an extremely difficult memory exam that only people with particular kind of brain can do.

[deleted]

Re: Taxi drivers rarely die of Alzheimer's

#16
Guys... Alzheimer's is 60-80% heritable, and driven largely by APOE genotype. No, you cannot get out of it with One Quick Trick. We have to find therapeutics to make real progress here.

This kind of misdirection is not helpful to the research community, or encouraging politicians to fund effective projects. Everyone WANTS a quick lifestyle change and will latch onto these things, but this is a real biological disease that needs real molecular fixes. Sorry, it's just how it is.

Re: Taxi drivers rarely die of Alzheimer's

#17

> In one landmark 2000 study, neuroscientists compared the brains of licensed London taxi drivers with those of people who did not drive cabs. Location is very important here. London cabbies have to pass The Knowledge which is an extremely difficult memory exam that only people with particular kind of brain can do.

Indeed. Elsewhere in the world taxi drivers just follow the GPS.

We had taxis long before GPS.

When I was in my early 20s I had a job delivering pizza. I very quickly learned the delivery area, I knew pretty much every street and alleyway and shortcut to get from one place to another. Much smaller than London but I think the human brain is very good at remembering routes and where things are in an area, as this would have been an evolutionary advantage (go out hunting and be able to find your way back). No GPS, didn't even carry a map with me. We had a large map on the wall at the store, and if I had to deliver to a street I didn't recognize I'd find it on the map, see where it was relative to the streets I did know, and then I never had any problem finding places.

Re: Taxi drivers rarely die of Alzheimer's

#19

Guys... Alzheimer's is 60-80% heritable, and driven largely by APOE genotype. No, you cannot get out of it with One Quick Trick. We have to find therapeutics to make real progress here. This kind of misdirection is not helpful to the research community, or encouraging politicians to fund effective projects. Everyone WANTS a quick lifestyle change and will latch onto these things, but this is a real biological disease…

Half of people with Alzheimer's carry at least one APOE ε4 allele. However, a full quarter of the population carries that mutation, and most carriers never go on to develop Alzheimer's. Lifestyle matters a lot here.

This kind of misdirection is not helpful for educating people on changes they can make now to reduce their risk, rather than waiting for a silver bullet. Alzheimer's research is well-funded in the US as the octogenarians running our congress are personally invested in it.

Re: Taxi drivers rarely die of Alzheimer's

#20
post #5

Seems strange to me that a specific type of thinking could influence something where most causes being investigated are physical

Unless the arrow of causality is the other way: those that would tend to develop memory problems do not become or remain as Taxi drivers.
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