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Training mRNA Language Models Across 25 Species for $165

news.ycombinator.com

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Re: Training mRNA Language Models Across 25 Species for $165

#12

Can someone explain what one might use this model for? As a developer with a casual interest in biology it would be fun to play with but honestly not sure what I would do

You can get your feet wet with genetic engineering for surprisingly little money.

This guy shows a lot of how it's done: https://www.youtube.com/@thethoughtemporium

Basically you can design/edit/inject custom genes into things and see real results spending on the scale of $100-$1000.

Re: Training mRNA Language Models Across 25 Species for $165

#13

What makes these Domain specific models work when we don’t have good domain models for health care, chemistry, economics and so on

>we don’t have good domain models for health care, chemistry, economics and so on

Who says we don't?

Re: Training mRNA Language Models Across 25 Species for $165

#14

What makes these Domain specific models work when we don’t have good domain models for health care, chemistry, economics and so on

>we don’t have good domain models for health care, chemistry, economics and so on Who says we don't?

Examples please?

Re: Training mRNA Language Models Across 25 Species for $165

#15

Can someone explain what one might use this model for? As a developer with a casual interest in biology it would be fun to play with but honestly not sure what I would do

You can get your feet wet with genetic engineering for surprisingly little money. This guy shows a lot of how it's done: https://www.youtube.com/@thethoughtemporium Basically you can design/edit/inject custom genes into things and see real results spending on the scale of $100-$1000.

Is there something like this in text/readable format?

Re: Training mRNA Language Models Across 25 Species for $165

#16
post #6

> In Progress: CodonJEPA JEPA is going to break the whole industry :D

Can you explain this? I haven't heard of JEPA, and from a quick search it seems to be vision/robotics based?

It’s a self supervised learning architecture, and it’s pretty much universal. The loss function runs on embeddings, and some other smart architectural choices allover. Worth diving into for a few hours, Yann LeCun gives some interesting talks about it

Re: Training mRNA Language Models Across 25 Species for $165

#17
post #5
post #2

full article: https://huggingface.co/blog/OpenMed/training-mrna-models-25-...

What makes this dataset or problem worth solving compared to other health datasets? Would the results on this task be broadly useful to health?

What other "datasets" are you talking about? How do you "solve a dataset" ?

Re: Training mRNA Language Models Across 25 Species for $165

#18

Earlier quoted context omitted.

>we don’t have good domain models for health care, chemistry, economics and so on Who says we don't?

Examples please?

No, it's really simple to search for domain specific models being used "in production" all over the place

Re: Training mRNA Language Models Across 25 Species for $165

#19

Earlier quoted context omitted.

Examples please?

No, it's really simple to search for domain specific models being used "in production" all over the place

I didn’t find a single one that outperforms a general model.

Re: Training mRNA Language Models Across 25 Species for $165

#20

Earlier quoted context omitted.

No, it's really simple to search for domain specific models being used "in production" all over the place

I didn’t find a single one that outperforms a general model.

Ok, alphafold.
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