interesting and well written article. I would imagine what you eat, amount of saliva, dental hygiene, and a lot of other variables would affect your oral microbiome. what would be a better test is for people with "red complex" bacteria to take this and see the results. the fact that it didn't colonize tells me this is pretty much useless like most probiotics https://medicine.tufts.edu/news-events/news/are-probiotics-a...
the author concluded that they will use it again only because of the taste, not because it works.
Oral microbiome sequencing after taking probiotics
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Re: Oral microbiome sequencing after taking probiotics
#12Wasn't there recently a discussion of a risk of methanol formation from an ethanol producing strain? I sure hope that none of your strains produce ethanol.
Re: Oral microbiome sequencing after taking probiotics
#13PSA: If a probiotic is on the shelf, not in a cooler, it's probably not worth buying. The best companies certify the count of organisms at time of manufacture , but no counts are guaranteed at the shelf. Probiotics are living organisms and ought to be refrigerated for max lifespan. You can get refrigerated probiotic supps at a place like Whole Foods. Source: I used to work in the industry.
does this apply universally to bacterial strains ?
Re: Oral microbiome sequencing after taking probiotics
#14PSA: If a probiotic is on the shelf, not in a cooler, it's probably not worth buying. The best companies certify the count of organisms at time of manufacture , but no counts are guaranteed at the shelf. Probiotics are living organisms and ought to be refrigerated for max lifespan. You can get refrigerated probiotic supps at a place like Whole Foods. Source: I used to work in the industry.
does this apply universally to bacterial strains ?
Yes
Re: Oral microbiome sequencing after taking probiotics
#15I would love to see this same analysis with a gut probiotic! I am never convinced if I'm wasting my money, which strains are best, should I do refrigerated or shelf-stable, etc.
As far as I am aware, fiber has infinitely superior research behind it with far more drastic effects. Just take fiber if you're worried about gut health imo.
Re: Oral microbiome sequencing after taking probiotics
#16PSA: If a probiotic is on the shelf, not in a cooler, it's probably not worth buying. The best companies certify the count of organisms at time of manufacture , but no counts are guaranteed at the shelf. Probiotics are living organisms and ought to be refrigerated for max lifespan. You can get refrigerated probiotic supps at a place like Whole Foods. Source: I used to work in the industry.
There are some newer types of probiotics (called "spore-based") which claim better shelf stability (don't require refrigeration) and resistance (to populate further down the digestive system). But you're absolutely right, they tend to die off pretty quickly (be extra weary of ordering them online, especially during the summer if they're going to sit around in a hot delivery truck or mailbox!).
Re: Oral microbiome sequencing after taking probiotics
#17This article is basically cargo cult biotech.
Re: Oral microbiome sequencing after taking probiotics
#18I want this for nasal microbiome. I think modern living is wreaking havoc on our upper respiratory track. We need to find a way to regenerate or improve nasal cavity microbiome.
Re: Oral microbiome sequencing after taking probiotics
#19This article is basically cargo cult biotech.
Tech bro woo at its finest. Can’t wait until they discover crystals.
Re: Oral microbiome sequencing after taking probiotics
#20the supplement industry is ridiculously sketchy and virtually unregulated wild-west
and probiotics are the absolute worst of the industry with endless lies in claims and products that often test with nothing of the claim in them
if you want to try probiotics
1. start with a single strain probiotic, multi-strain are often lies
2. try an extremely well known/proven probiotic
want to know something is happening? try lp299v Lactobacillus Plantarum
it's cheap, it's been studied for 30+ years so lots of trials and proven claims
it won't colonize, no oral probiotic will colonize, so you have to keep taking it or it's gone in a few days from your GI