Live data from Hacker News

Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

researchsquare.com

11–20 of 147 posts

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#12
post #6

This is (probably) not a Long Covid story but I found that bloodletting (for which I even received money!) gave me back the energy that I was missing for the last few years (e.g. it was impossible to build stamina). I also read about a study about the positive effects of bloodletting[1] that somehow is not all the rage in mainstream news, which I find perplexing. If it might be so easy to improve your health (for som…

If this were the case you could do a natural study on this by comparing menstruating women with the rest of the population

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#13

The paper claims that 1/5 of people experience Long COVID after an infection. Given that approximately everyone has caught COVID by now, this does not track with how rarely I've heard of people with it. Wikipedia lists much lower numbers on https://en.wikipedia.org/wiki/Long_COVID (6–7% in adults, ~1% in children, less after vaccination.) and seems to use a more liberal definition than this paper, as it mentions "Mos…

Could it be that you can have different severity of long covid? Someone with very severe symptoms will notice it but someone with small symptoms might not realise it (and instead think they are just less fit)

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#14
Edit - this comment is incorrect

---

The title should be edited. It sounds as if the test is 94% accurate at detecting long covid, but in fact it's 94% accurate at counting microclots

> We estimated a 94% accuracy for the microclot count using the devices, significantly higher than the traditional counting of microclots on slides (66% accuracy)

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#15
post #12
post #6

This is (probably) not a Long Covid story but I found that bloodletting (for which I even received money!) gave me back the energy that I was missing for the last few years (e.g. it was impossible to build stamina). I also read about a study about the positive effects of bloodletting[1] that somehow is not all the rage in mainstream news, which I find perplexing. If it might be so easy to improve your health (for som…

If this were the case you could do a natural study on this by comparing menstruating women with the rest of the population

This has been done. Women seem to have certain health benefits that stop after menopause. Reading about it was the first time I wondered whether blood letting made sense.

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#16

94% accuracy sounds extremely bad, no? https://www.ssph-journal.org/journals/public-health-reviews/... > Prevalence estimated (...) 2%–3.5% in primarily non-hospitalized children. So a fake test always saying "No" would be more accurate at 96.5% accuracy.

The sensitivity of such a test would be 0. This test had a sensitivity of 91% versus 61% for the glass slide count method, which is a large improvement.

The sample size is pretty small here and the control group even smaller. The paper concludes that a larger study is necessary to confirm the result.

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#17
post #6

This is (probably) not a Long Covid story but I found that bloodletting (for which I even received money!) gave me back the energy that I was missing for the last few years (e.g. it was impossible to build stamina). I also read about a study about the positive effects of bloodletting[1] that somehow is not all the rage in mainstream news, which I find perplexing. If it might be so easy to improve your health (for som…

[deleted]

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#18
post #3

Can someone knowledgeable explain the current understanding of Covid’s long time effects? I thought it was still a big unknown and long COVID was still debated as to even having a clear definition.

If only there were some sort of link here with that sort of information!

I did read the article. It only talks about detecting long covid in children, which is different to understanding its effect on adults and the long terms effect of COVID in general (vs long COVID, which if understand correctly it’s a different syndrome to just “ long term expected outcomes from having had COVID”).

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#19

Can they disambiguate between spike protein microclots produced by natural infection vs. those generated by the vaccines.

I am curious about the working hypothesis leading to this question.

Hypothesis: microclots are caused by the viral spike protein. The mRNA vaccine produces the viral spike protein. Therefore, a non-zero percentage of microclots are caused by spike protein originating from the vaccine.

Re: Quantification of fibrinaloid clots in plasma from pediatric Long COVID patients

#20

Can they disambiguate between spike protein microclots produced by natural infection vs. those generated by the vaccines.

I am curious about the working hypothesis leading to this question.

One of the working theories on people suffering long COVID-like symptoms after receiving an mRNA COVID vaccine may apparently be related to spike proteins found in the patient's blood far longer than is typical/intended. This is apparently similar to long COVID patients.

At least, that's my layman's understanding when I was following it some years ago. I'm not sure if there's been more recent studies that have found more concrete links since then, but I suspect GP is in the same boat, which is why they asked.

Post reply on HN