Neat project I do wonder what more could be done with the RP2350.
Note that the RP2350, being M33 based has square root, and can add 16MB of PSRAM behind the XIP that will help with the flash writing problem, The solder party RP2350 Stamp XL has a SOP8 pad to add PSRAM and is actually shipping for anyone who is looking to play with them, no connection with them, just a user.
The extra PIO block would also allow for S2C output which may be nice rather than a TPA2012D2, which will require most people to buy a breakout board anyway.
The rp2040/rp2350 series is incredible. The DMA/SIO/PIO features are just so powerful and even the esp32/stm32 seem restrictive to me to go back to. It is amazing what people are doing with them.