Live data from Hacker News

FDA Approves drug to treat pain without opioid effects

nytimes.com

11–20 of 34 posts

Re: FDA Approves drug to treat pain without opioid effects

#12
post #6

Super exciting development in the world of medicine, but the price tag is really steep. Starting at US$15.50 per pill, and you're supposed to take two pills at a time. Many will opt for cheaper options. Disclaimer: I'm Canadian with extended insurance, so I have little perspective on drug prices.

If it means staying away from addiction, I'll pay it. Opiods would scare me if I ever needed that level of pain treatment.

[deleted]

Re: FDA Approves drug to treat pain without opioid effects

#14
post #6

Super exciting development in the world of medicine, but the price tag is really steep. Starting at US$15.50 per pill, and you're supposed to take two pills at a time. Many will opt for cheaper options. Disclaimer: I'm Canadian with extended insurance, so I have little perspective on drug prices.

This is to treat acute pain, probably mostly post-op as alternative to opioids. At most you'll probably get a week's worth of pills from your doc post-op, and I would say the cost is worth it if it works better than NSAIDs and it's not addictive.

Can this be taken alongside NSAIDs? If so it might not even need to be that great to still be worthwhile for that first week after an operation.

Re: FDA Approves drug to treat pain without opioid effects

#16
post #6

Super exciting development in the world of medicine, but the price tag is really steep. Starting at US$15.50 per pill, and you're supposed to take two pills at a time. Many will opt for cheaper options. Disclaimer: I'm Canadian with extended insurance, so I have little perspective on drug prices.

My Armodafinil Rx cost $35/pill — not covered by insurance.

Re: FDA Approves drug to treat pain without opioid effects

#17
post #6

Super exciting development in the world of medicine, but the price tag is really steep. Starting at US$15.50 per pill, and you're supposed to take two pills at a time. Many will opt for cheaper options. Disclaimer: I'm Canadian with extended insurance, so I have little perspective on drug prices.

If it means staying away from addiction, I'll pay it. Opiods would scare me if I ever needed that level of pain treatment.

They should, synthethic opioids are VERY enjoyable, VERY risky and SUPER addictive.

I was on Oxy 24/7 for a month following surgery, went through hell.

Re: FDA Approves drug to treat pain without opioid effects

#18

There's no reason for this to be a NYT link. https://www.fda.gov/news-events/press-announcements/fda-appr...

(2024) "Pharmacology and Mechanism of Action of Suzetrigine, a Potent and Selective NaV1.8 Pain Signal Inhibitor for the Treatment of Moderate to Severe Pain" (pdf)

https://link.springer.com/content/pdf/10.1007/s40122-024-006...

Re: FDA Approves drug to treat pain without opioid effects

#19
post #3

There's no reason for this to be a NYT link. https://www.fda.gov/news-events/press-announcements/fda-appr...

> "There's no reason for this to be a NYT link." I respectfully disagree. The NYT paid the author, Gina Kolata, to research and write the story, which contains more details than just the press release alone, then used their platform to made the news widely available and thus helped people like me discover it. As cynical as one may be about the state of contemporary journalism, I'd say that short articles like this ar…

Journalism on science and medicine gets more things wrong than right.

Re: FDA Approves drug to treat pain without opioid effects

#20
post #6

Super exciting development in the world of medicine, but the price tag is really steep. Starting at US$15.50 per pill, and you're supposed to take two pills at a time. Many will opt for cheaper options. Disclaimer: I'm Canadian with extended insurance, so I have little perspective on drug prices.

This is to treat acute pain, probably mostly post-op as alternative to opioids. At most you'll probably get a week's worth of pills from your doc post-op, and I would say the cost is worth it if it works better than NSAIDs and it's not addictive.

"It's worth it" isn't an answer to "drug prices are systematically inflated so many cannot afford them regardless.
Post reply on HN