Maybe it's similar to the idea that we can just eradicate mosquitos with no negative effects. Is that really true?
Engineering Sleep
11–20 of 205 posts
Re: Engineering Sleep
#12Both my parents go to bed around 1am and wake up at 7am, and so did all of my grandparents. My kids on weekends go to bed around 1-2am as well but do sleep in, and my average is about 4-5 hours a night…
As for me, I’ve had sleep issues all my life and found the only way to fall asleep within 20 minutes is to stay up until exhaustion. But lately I’ve been gaining back my time and pushing even further - once every one or two weeks I’ll skip a night of sleeping, staying up around 36 hours straight. I’ve been doing this for a few months now and have zero side effects so far. In fact I end up sleeping over 10 hours the next day without waking up in the middle (which /never/ happens otherwise).
Re: Engineering Sleep
#13How about — instead of making sleep more "efficient" — we engineer our lives to provide decent amount of sleep and not stress over having more and more of the waking hours to do stuff. After all, we live in the age of abundance . (Though I admit I might not be the best person to ask for this as I am on the lower end of how much sleep I need)
Re: Engineering Sleep
#14Why is it not a survival advantage? Probably because we didn't work 18 hour days, the extra wakeness would just be used for rest. Night shifts that anyone can do are still needed if you need tribal watchers, and normal 8hr sleeping people can wake upnand fight when needed. In terms of the gene, I am suprised how rare it is (90 families?) given I have met someone who needs only 4hr sleep. Another point is less sleep d…
Re: Engineering Sleep
#15How about — instead of making sleep more "efficient" — we engineer our lives to provide decent amount of sleep and not stress over having more and more of the waking hours to do stuff. After all, we live in the age of abundance . (Though I admit I might not be the best person to ask for this as I am on the lower end of how much sleep I need)
We could be sleeping less to do more fun stuff, no?
This isn't some kind of box ticking behaviour with its roots originating from toxic hustle culture, simply the adverse effects of sleep deprivation don't outweigh my enjoyment of things. And when my sleep debt finally catches up with me, I sleep my heart's delight.
From experience, I have friends who share in my world view and threshold for sacrificing sleep for pleasure and I have met people who think are mortified by this behaviour. My immediate family are all willing to sacrifice sleep on the drop of the hat notably - waking up at the crack of dawn to send/accompany someone to the airport is simply modus operandi. My wife is very keen to protect her sleep on the flipside and so when we travel together our decision frameworks need to accommodate both MOs
Ironically sometimes I'm most protective of my sleep during the weekly grind (and also training for fitness) because then my performance matters. If my only short term downside is discomfort from fatigue, I'll regularly trade that for more "uptime"
Re: Engineering Sleep
#16"The company ( FitBiomics ) has already commercialized two products. Their flagship offering, V•Nella, helps metabolize lactic acid and reduce fatigue, while Nella targets sleep health - a crucial market considering that 100 million Americans suffer from insomnia. "Within 10 to 14 days of daily consumption, consumers feel the difference," Scheiman notes. "They have less daily fatigue interfering with their daily life, more energy, and some people are tracking cardiovascular benefits on their wearables. We hear really cool anecdotal feedback like, 'Hey, I no longer have to take a nap in the middle of the day, or I no longer need coffee in the middle of the day.'"
Re: Engineering Sleep
#17If there was in fact a safe pathway to only needing 2 hours of sleep I would 100% use it and consider it a zero to one innovation. Although I think it would also come with a lot of pushback. One of my favourite questions to ask people is "if there was a way that allowed you to not sleep and be completely fine, would you take it?". Surprisingly (or maybe not) most people will answer no and say they like sleep to much.…
Of these, only dreaming strictly needs sleep, however, I think the healing that occurs in deep sleep should be added as a need.
And according to my smartwatch, I spend around 2 hours dreaming and 1 hour in deep sleep each night, although this varies quite a bit night to night. I don't think trying to reduce these is a good idea.
That means light sleep is the candidate for reduction. However, I have researched this before and the most consistent answer I get is that we don't really know what the 5 hours spent in light sleep is for. It seems unlikely that it's just for conserving energy, the body rarely does things for only one reason.
So my bet is that we might find a way to reduce light sleep by around 2 hours a night, which is what this article is suggesting. But it's unlikely that we'll go much further without causing problems. And even if someone does discover a way, there's no way I'd try it without at least a few decades of evidence that it doesn't cause Alzheimer's or some other old age disease.
Re: Engineering Sleep
#18The average day for me has huge differences in terms of my productivity at any given moment. I need downtime anyway, if I didn't sleep I believe that I'd end up vegging out in some way because I'm not doing 24 hours of flashcards.
The discussions on here also always seem to centre around a very stereotypical "I am a vat for my brain" way of thinking. Realistically whilst sleeping other things are going on, muscles are recovering, digestive processes are going on, other forms of growing, etc, it's not just the brain.
There are also things like circadian rhythm, sunshine, etc. I woke up early today and had a few hours of darkness, I can feel my mood and brainpower improving as the sun rises.
We are not bots, this stuff is analogue.
Re: Engineering Sleep
#19"preemptive administration of low-dose aspirin during sleep restriction reduced pro-inflammatory responses. Specifically, aspirin reduced interleukin-6 expression and COX-1/COX-2 double positive cells in lipopolysaccharide-stimulated monocytes, as well as C-reactive protein serum levels."
"aspirin-induced reduction of inflammatory pathway activity in sleep-restricted participants was paralleled by decreased wake after sleep onset and increased sleep efficiency during recovery sleep"
But, bleeding and strokes :(
https://medicalxpress.com/news/2024-06-dose-aspirin-inflamma...
Re: Engineering Sleep
#20So, one possible line of investigation would be a table of mammals, their sleep cycles, their orexin levels, and the numbers of copies of orexin and it's regulators in their genomes. For example: compared to humans, elephants have a lower cancer risk. Turns out they have significantly more copies of p53, a tumor supressor gene (1).
Perhaps a similar, somewhat parallel construct exists: elephants sleep 3-4 hours a night. Maybe they have more orexin? Maybe they have different copy numbers or mutations of the relevant genes in the pathway?