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I like how they aren't saying Semaglutide in the title in an attempt to perhaps keep it from immediate scrutiny.
https://www.fda.gov/drugs/postmarket-drug-safety-information... Same thing??
I like how they aren't saying Semaglutide in the title in an attempt to perhaps keep it from immediate scrutiny.
https://www.fda.gov/drugs/postmarket-drug-safety-information... Same thing??
That's the sort of headlines that smells like bullshit to me.
My understand of those drugs is that they don't actually make you lose weight, they just cut your appetite so you can follow a diet to lose weight without hunger hammering at the door. So to start with, if that's the case, all they are observing is the effect of a diet. Not sure the diet drug has much to do with it.
Then I went from 133kg to 88kg with these diet drugs. Even though I exercised every day, I am sure I also lost some muscle mass as well, just because I don't have to carry 45kg every time I make a move anymore. Seems logical and would probably be concerned if it was any other way.
It seems the article isn't just saying it's heart muscle that's being lost but regular muscle in general. Even more so than in a low calorie diet.
>Studies suggest muscle loss with these medications (as indicated by decreases in fat-free mass [FFM]) ranges from 25% to 39% of the total weight lost over 36–72 weeks. This substantial muscle loss can be largely attributed to the magnitude of weight loss, rather than by an independent effect of GLP-1 receptor agonists, although this hypothesis must be tested. By comparison, non-pharmacological caloric restriction studies with smaller magnitudes of weight loss result in 10–30% FFM losses.
Comparing weight loss of different magnitudes is kind of comparing apples to oranges. Of course, it's not really possible to get persistent, large magnitude weight loss any other way than by using these drugs, so I understand why the comparison was made.
Have only lived a few decades on this planet and the weight loss trends with pharmaceuticals is wild.
I like how they aren't saying Semaglutide in the title in an attempt to perhaps keep it from immediate scrutiny.
As a coder, I'm realising more and more that the human body isn't so different from a computer. When you try to fix something without having complete understanding of all the relevant parts of the system, you will invariably introduce new issues. With a machine as complex as the human body, it seems inevitable that the field of medicine would be a game of whac-a-mole. Finding solutions which don't create new problems…
> emerging research showing that up to 40 per cent of the weight lost by people using weight-loss drugs is actually muscle That's the sort of headlines that smells like bullshit to me. My understand of those drugs is that they don't actually make you lose weight, they just cut your appetite so you can follow a diet to lose weight without hunger hammering at the door. So to start with, if that's the case, all they are…