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Drinking alcohol reduces the body's natural GLP-1 activity by 34%

recursiveadaptation.com

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Re: Drinking alcohol reduces the body's natural GLP-1 activity by 34%

#11

Post by dzhiurgis »

tredre3 wrote: post #7
AtlasBarfed wrote: post #6

Earlier quoted context omitted.

The double whammy is that alcohol is an extremely calorically dense substance. Even worse, it is consumed in liquid form, which also bypasses some satiation mechanisms in the body. There's a reason tour de France riders get most of their replacement calories in liquid form

Indeed the average base spirit has 2-3 calorie per millilitre. This is 5-6x the amount found in coca cola or pepsi. But then again, the quantities are also much less than when drinking soft drinks (hopefully).

IDK I can down a sixpack or two pretty easily. I can’t imagine drinking so much soda or even water.

Re: Drinking alcohol reduces the body's natural GLP-1 activity by 34%

#13

Post by squidgedcricket »

tredre3 wrote: post #7
AtlasBarfed wrote: post #6

Earlier quoted context omitted.

The double whammy is that alcohol is an extremely calorically dense substance. Even worse, it is consumed in liquid form, which also bypasses some satiation mechanisms in the body. There's a reason tour de France riders get most of their replacement calories in liquid form

Indeed the average base spirit has 2-3 calorie per millilitre. This is 5-6x the amount found in coca cola or pepsi. But then again, the quantities are also much less than when drinking soft drinks (hopefully).

Glucose and ethanol are metabolized through different pathways that will have different efficiencies. How much impact does that have on comparing the two?

Glucose can go right into the bloodstream (?), but ethanol needs to be reacted (taking energy) to turn into blood glucose.

This is a confusion I have about calories-in-calories-out in general, fat/carbs/protein are all metabolized with different (and variable) efficiencies. Even pro-CICO folks agree not to count ingested calories that can't be metabolized, but that's just one spot on a gradient to draw a line.

Re: Drinking alcohol reduces the body's natural GLP-1 activity by 34%

#14

Post by tguvot »

dzhiurgis wrote: post #11
tredre3 wrote: post #7

Earlier quoted context omitted.

Indeed the average base spirit has 2-3 calorie per millilitre. This is 5-6x the amount found in coca cola or pepsi. But then again, the quantities are also much less than when drinking soft drinks (hopefully).

IDK I can down a sixpack or two pretty easily. I can’t imagine drinking so much soda or even water.

you can down a sixpack or two of stout or hoegaarden ?

Re: Drinking alcohol reduces the body's natural GLP-1 activity by 34%

#16

Post by tiffanyh »

ipaddr wrote: post #10
tiffanyh wrote: post #5

Which is interesting because there’s a lot of Mediterranean cultures that drink after every meal (lunch & dinner). And the reason is “for digestion”. So this would suggest the opposite effect is happening. Drinking actually hurts digestion.

Fermenting grapes is different than any alcohol.

I wasn’t thinking wine.

More like Ouzo in Greece.

https://en.wikipedia.org/wiki/Ouzo#:~:text=Ouzo%2520(Greek%2....

Re: Drinking alcohol reduces the body's natural GLP-1 activity by 34%

#17

Post by someonehere »

comova wrote: post #3

And if you haven't asked a friend who's on one, taking a GLP-1 medication reduces drinking by about 50%: https://recursiveadaptation.com/p/first-ever-randomized-tria...

Can confirm I can’t drink as much anymore and have switched to Lite beers because I don’t feel weird after drinking.

Re: Drinking alcohol reduces the body's natural GLP-1 activity by 34%

#18

Post by resoluteteeth »

ipaddr wrote: post #10
tiffanyh wrote: post #5

Which is interesting because there’s a lot of Mediterranean cultures that drink after every meal (lunch & dinner). And the reason is “for digestion”. So this would suggest the opposite effect is happening. Drinking actually hurts digestion.

Fermenting grapes is different than any alcohol.

Is it? There has been a lot of research on stuff like antioxidants in wine but as far as I can tell that's largely because of older observational health studies on purporting to show a positive effect from moderate wine consumption which has disappeared in more recent studies that did a better job controlling for confounding factors (like many people who don't drink at all being former alcoholics or having other health issues) which have shown that any alcohol consumption is harmful.

Re: Drinking alcohol reduces the body's natural GLP-1 activity by 34%

#19

Post by dzhiurgis »

tguvot wrote: post #14
dzhiurgis wrote: post #11

Earlier quoted context omitted.

IDK I can down a sixpack or two pretty easily. I can’t imagine drinking so much soda or even water.

you can down a sixpack or two of stout or hoegaarden ?

Not really. I prefer IPA. It’s a nice benefit you need less of those.

Re: Drinking alcohol reduces the body's natural GLP-1 activity by 34%

#20

Post by kjellsbells »

tiffanyh wrote: post #5

Which is interesting because there’s a lot of Mediterranean cultures that drink after every meal (lunch & dinner). And the reason is “for digestion”. So this would suggest the opposite effect is happening. Drinking actually hurts digestion.

The digestif isnt the wine you drink at dinner though, it's the (different) wine you drink after dinner, and it really is very different. For example: small prosecco before dinner, then red or white wine with the food, and then a Fernet Branca at the end of the meal.

Digestifs seem to often have a bitter or aniseed element in them. I wonder if that is now known to have a legitimate scientific basis, or if it's just some kind of Mediterranean historical accident.

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