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Ozempic could delay ageing, researchers suggest

bbc.com

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Re: Ozempic could delay ageing, researchers suggest

#11

Post by AlexandrB »

nikkwong wrote: post #10
heraldgeezer wrote: post #6

Is this due to the drug itself or due to eating less? Another tip is to stay out of the sun.

*Another tip is to stay in the sun. The data on sun exposure has largely reversed over the last decade; sun exposure is positively correlated with improved health outcomes, but should be done in moderation as to prevent skin issues.

Where "moderation" means something like 15-30 minutes[1].

[1] https://www.webmd.com/a-to-z-guides/ss/slideshow-sunlight-he...

Re: Ozempic could delay ageing, researchers suggest

#12

Post by dirtdobber »

nikkwong wrote: post #10
heraldgeezer wrote: post #6

Is this due to the drug itself or due to eating less? Another tip is to stay out of the sun.

*Another tip is to stay in the sun. The data on sun exposure has largely reversed over the last decade; sun exposure is positively correlated with improved health outcomes, but should be done in moderation as to prevent skin issues.

It turns out that food is also healthy for you, in moderation. Alas, we need a drug to help us moderate.

Re: Ozempic could delay ageing, researchers suggest

#15

Post by r00fus »

rapsey wrote: post #14
pokstad wrote: post #13

Earlier quoted context omitted.

Doesn’t Ozempic have a bunch of serious side effects besides weight loss?

Side effect is also losing muscle mass

People who are overweight have much more muscle mass than people who normal weight.

Losing that muscle mass is normal

Re: Ozempic could delay ageing, researchers suggest

#16

Post by rendaw »

smt88 wrote: post #3
Mistletoe wrote: post #2

> The studies - part of the Select trial - tracked more than 17,600 people, aged 45 or older, as they were given either 2.4 mg of semaglutide or a placebo for more than three years. Participants were obese or overweight and had cardiovascular disease but not diabetes. Exciting stuff. What does data look like in people that aren’t obese?

Calorie restriction is a well-studied (though not terribly healthy) way to slow aging. It's likely these drugs are just making it easier for people.

I thought calorie restriction was another order of magnitude, beyond "normal" weight. But I guess if obesity was causing accelerated ageing, you could say not being obese is delaying ageing.

Re: Ozempic could delay ageing, researchers suggest

#18

Post by declan_roberts »

r00fus wrote: post #15
rapsey wrote: post #14

Earlier quoted context omitted.

Side effect is also losing muscle mass

People who are overweight have much more muscle mass than people who normal weight. Losing that muscle mass is normal

Fat guys can do incredible leg press and calf raise numbers.

Re: Ozempic could delay ageing, researchers suggest

#19

Post by smt88 »

woleium wrote: post #9
smt88 wrote: post #3

Earlier quoted context omitted.

Calorie restriction is a well-studied (though not terribly healthy) way to slow aging. It's likely these drugs are just making it easier for people.

See Roy Walford et al out of UCLA on the CRON diet. Its not a nice way to live, but it seems to be safe and healthy.

I'll have to look into it more, but from what I've seen, it seemed that people had to restrict calories so much that their immune system was underactive (which may be a large part of why it works).

Re: Ozempic could delay ageing, researchers suggest

#20

Post by smt88 »

rendaw wrote: post #16
smt88 wrote: post #3

Earlier quoted context omitted.

Calorie restriction is a well-studied (though not terribly healthy) way to slow aging. It's likely these drugs are just making it easier for people.

I thought calorie restriction was another order of magnitude, beyond "normal" weight. But I guess if obesity was causing accelerated ageing, you could say not being obese is delaying ageing.

It varies from study to study, but generally what I've seen for anti-aging is ~1,000 calories per day or less. I've seen it as low as 500.
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