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Tripping on Xenon Gas (2023)

tripsitter.substack.com

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Re: Tripping on Xenon Gas (2023)

#11

Post by schoen »

lpribis wrote: post #7
IsTom wrote: post #3

Wouldn't it be the same as breathing any other nonreactive gas? Isn't this just symptoms of hypoxia?

No, xenon is a NMDA antagonist meaning it has dissociative/anaesthetic effects like ketamine or nitrous oxide. TFA talks about the effects coming on "within seconds" of inhalation, so it is clearly not just hypoxia which takes tens of seconds or minutes to manifest.

How does it do that without forming chemical compounds? Is it like a catalyst for another reaction or something?

Re: Tripping on Xenon Gas (2023)

#12

Post by pengaru »

IsTom wrote: post #3

Wouldn't it be the same as breathing any other nonreactive gas? Isn't this just symptoms of hypoxia?

I'm fairly certain when administered medically it's a controlled mix of oxygen and xenon, like nitrous at the dentist. They're not asphyxiating you, these molecules are psychoactive.

Re: Tripping on Xenon Gas (2023)

#14

Post by dyauspitr »

IsTom wrote: post #3

Wouldn't it be the same as breathing any other nonreactive gas? Isn't this just symptoms of hypoxia?

I do the Wim Hof breathing exercise that involves up to 15 seconds of hypoxia. I get a pretty significant head change from it. Hopefully I’m not causing any permanent damage.

Re: Tripping on Xenon Gas (2023)

#16

Post by rvba »

> Xenon is unique among psychedelic drugs because it’s a pure element. It leaves the body exactly as it entered, completely unchanged.

I very doubt it is true. The article poorly hand waves later that a brain without oxygen will starve.

I bet shooting this crap for some short term high will burn your brain cells, even if mixed with oxygen.

Re: Tripping on Xenon Gas (2023)

#17

Post by smabie »

perihelions wrote: post #10

[flagged]

Couldn't you say the same about any extreme activity (like going to the moon or base jumping or extreme stuntmen etc)?

Some people seek out risk because it makes life worth living.

Life is finite anyways so even if you are very careful you'll end up dead just like the rest of us.

Re: Tripping on Xenon Gas (2023)

#18

Post by teraflop »

schoen wrote: post #11
lpribis wrote: post #7

Earlier quoted context omitted.

No, xenon is a NMDA antagonist meaning it has dissociative/anaesthetic effects like ketamine or nitrous oxide. TFA talks about the effects coming on "within seconds" of inhalation, so it is clearly not just hypoxia which takes tens of seconds or minutes to manifest.

How does it do that without forming chemical compounds? Is it like a catalyst for another reaction or something?

Even though xenon doesn't easily form "compounds" in the normal chemical sense, it does weakly interact with other molecules through van der Waals forces, which are strong enough to affect the functioning of various receptors in neurons.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467505/

Re: Tripping on Xenon Gas (2023)

#19

Post by duskwuff »

schoen wrote: post #11
lpribis wrote: post #7

Earlier quoted context omitted.

No, xenon is a NMDA antagonist meaning it has dissociative/anaesthetic effects like ketamine or nitrous oxide. TFA talks about the effects coming on "within seconds" of inhalation, so it is clearly not just hypoxia which takes tens of seconds or minutes to manifest.

How does it do that without forming chemical compounds? Is it like a catalyst for another reaction or something?

I'm not an expert on the biochemistry, but Wikipedia has a summary of some of the known interactions at:

https://en.wikipedia.org/wiki/Xenon#Anesthesia

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