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Novel drug could protect brains from damage after repeat concussions

medicalxpress.com

11–20 of 108 posts

Re: Novel drug could protect brains from damage after repeat concussions

#11
> A 54-g metal (tungsten) bolt was used to deliver an impact to the dorsal aspect of the skull, resulting in a rotational acceleration of the head through the Kimwipe. Mice underwent seven repetitive less-than-mild injuries (rlmTBI, 24-inch height; W/5 mm flat) OR repetitive mild injuries (rmTBI, 36-inch height; W/5 mm flat) in 9 days.

This seems very cruel, even in the face of progress. The price that animals pay for human survival is unimaginable.

Re: Novel drug could protect brains from damage after repeat concussions

#12

If you end up taking a drug because someone bangs you on your head everyday, it's good that it's there, but you might also want to put a stop to that.

As far as I know there aren’t any sports which are completely safe and without side effects. Sport can ruin your joints (eg. running), spine (eg. weightlifting) and cause plethora of other health issues (anecdotally I know many people who got serious injuries from while leisurely playing team games).

Usually there’s net gain from those activities, and what sport one practices vastly depends on preference and I’d rather encourage people to get hit in the head in controlled environment versus growing roots in the chair.

As a fan of practicing fighting sports I find such drug a great addition to all the other protection amateur can have.

Re: Novel drug could protect brains from damage after repeat concussions

#13

Earlier quoted context omitted.

Perhaps, but many sports (such as football and American football) are far too popular to end anytime soon. Additionally, it may be given as a precaution after a first concussion (car wreck, for example), even if that person is unlikely to be "banged on the head everyday"

https://www.nfl.com/news/op-ed-flag-football-can-t-be-ignore... https://news.ycombinator.com/item?id=39081597

Sorry, no one is gonna prefer to watch flag football over full contact tackling. This is an absurd article. And the fact that the Olympics are holding a flag football event is a joke.

Re: Novel drug could protect brains from damage after repeat concussions

#14

> A 54-g metal (tungsten) bolt was used to deliver an impact to the dorsal aspect of the skull, resulting in a rotational acceleration of the head through the Kimwipe. Mice underwent seven repetitive less-than-mild injuries (rlmTBI, 24-inch height; W/5 mm flat) OR repetitive mild injuries (rmTBI, 36-inch height; W/5 mm flat) in 9 days. This seems very cruel, even in the face of progress. The price that animals pay fo…

[deleted]

Re: Novel drug could protect brains from damage after repeat concussions

#15

> A 54-g metal (tungsten) bolt was used to deliver an impact to the dorsal aspect of the skull, resulting in a rotational acceleration of the head through the Kimwipe. Mice underwent seven repetitive less-than-mild injuries (rlmTBI, 24-inch height; W/5 mm flat) OR repetitive mild injuries (rmTBI, 36-inch height; W/5 mm flat) in 9 days. This seems very cruel, even in the face of progress. The price that animals pay fo…

I'd take it further, in my opinion, it is essentially unjustifiable in a deeply karmic way.

I genuinely think that I would be able to work on a weapons guidance system and even know that it has been used to target a military vehicle without feeling much guilt but performing the kind of work you have quoted on animals would make me stop and think. And just stop. It is not worth the progress. Not worth the credits, the money. Not worth graduating.

Re: Novel drug could protect brains from damage after repeat concussions

#16

> A 54-g metal (tungsten) bolt was used to deliver an impact to the dorsal aspect of the skull, resulting in a rotational acceleration of the head through the Kimwipe. Mice underwent seven repetitive less-than-mild injuries (rlmTBI, 24-inch height; W/5 mm flat) OR repetitive mild injuries (rmTBI, 36-inch height; W/5 mm flat) in 9 days. This seems very cruel, even in the face of progress. The price that animals pay fo…

Science does not hide the suffering it causes, unlike, for example, food production or pest control. Hence, people often react with shock when confronted with the reality of animal experiments needed for medical progress.

Re: Novel drug could protect brains from damage after repeat concussions

#18

Earlier quoted context omitted.

https://www.nfl.com/news/op-ed-flag-football-can-t-be-ignore... https://news.ycombinator.com/item?id=39081597

Sorry, no one is gonna prefer to watch flag football over full contact tackling. This is an absurd article. And the fact that the Olympics are holding a flag football event is a joke.

That's what the Romans said when they tried to go from fighting to the death to fighting until someone yielded.

Re: Novel drug could protect brains from damage after repeat concussions

#19
post #15

> A 54-g metal (tungsten) bolt was used to deliver an impact to the dorsal aspect of the skull, resulting in a rotational acceleration of the head through the Kimwipe. Mice underwent seven repetitive less-than-mild injuries (rlmTBI, 24-inch height; W/5 mm flat) OR repetitive mild injuries (rmTBI, 36-inch height; W/5 mm flat) in 9 days. This seems very cruel, even in the face of progress. The price that animals pay fo…

I'd take it further, in my opinion, it is essentially unjustifiable in a deeply karmic way. I genuinely think that I would be able to work on a weapons guidance system and even know that it has been used to target a military vehicle without feeling much guilt but performing the kind of work you have quoted on animals would make me stop and think. And just stop. It is not worth the progress. Not worth the credits, the…

The people conducting this kind of research pay an emotional price for it. Here is a very thoughtful account of how it can affect you:

https://www.cnet.com/science/i-killed-563-mice-for-science/

I did this myself for many years, and honestly, I believe the world would be a better place if the people designing weapons were exposed to the suffering they cause to the same degree we are.

Re: Novel drug could protect brains from damage after repeat concussions

#20
post #12

If you end up taking a drug because someone bangs you on your head everyday, it's good that it's there, but you might also want to put a stop to that.

As far as I know there aren’t any sports which are completely safe and without side effects. Sport can ruin your joints (eg. running), spine (eg. weightlifting) and cause plethora of other health issues (anecdotally I know many people who got serious injuries from while leisurely playing team games). Usually there’s net gain from those activities, and what sport one practices vastly depends on preference and I’d rath…

Swimming?
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