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Confocal microscopy

en.wikipedia.org

11–20 of 22 posts

Re: Confocal microscopy

#12

Not sure why this article made it to front page, but fwiw, I used to work as a research engineer in a role where using a confocal microscope in clinical trial settings was a regular part of my job. AMA :D

What use cases? I had my cornea scanned with it when it was damaged some years ago. I didn't appreciate that it had to be touching it.

Re: Confocal microscopy

#14
I was offered a 3d laserscanning microscope that combines confocal microscopy with interferometry. Manufacturer claims resolution "up to 0,01nm", (10pm), not a typo. That is quite remarkable if true but I wonder what that even means...

Re: Confocal microscopy

#15
post #14

I was offered a 3d laserscanning microscope that combines confocal microscopy with interferometry. Manufacturer claims resolution "up to 0,01nm", (10pm), not a typo. That is quite remarkable if true but I wonder what that even means...

I'm guessing provided you have a dilute enough solution, it will tell you where particles that small are, but you won't actually be able to "see" them.

Re: Confocal microscopy

#16
post #15
post #14

I was offered a 3d laserscanning microscope that combines confocal microscopy with interferometry. Manufacturer claims resolution "up to 0,01nm", (10pm), not a typo. That is quite remarkable if true but I wonder what that even means...

I'm guessing provided you have a dilute enough solution, it will tell you where particles that small are, but you won't actually be able to "see" them.

They seem to target quality control in manufacturing (semiconductor, electronics etc...). What is puzzling to me is that even your typical atom is an order of magnitude larger than that claimed resolution.

Re: Confocal microscopy

#17
post #10

Used to work in the Oxford lab that developed some of the earliest confocal microscopes. I had one of the early Oxford instruments mentioned under my table. Always wondered why it didn't find it's way to a museum. Science historical artifacts aren't a huge field of history yet I guess and items only a few decades old aren't that exciting to the average person. Technology becomes ancient faster than anything else.

The History of Science Museum on Broad Street actually has a microscope collection. I can imagine they'd be interested, if they've got the space.

Re: Confocal microscopy

#18
post #10

Used to work in the Oxford lab that developed some of the earliest confocal microscopes. I had one of the early Oxford instruments mentioned under my table. Always wondered why it didn't find it's way to a museum. Science historical artifacts aren't a huge field of history yet I guess and items only a few decades old aren't that exciting to the average person. Technology becomes ancient faster than anything else.

The History of Science Museum on Broad Street actually has a microscope collection. I can imagine they'd be interested, if they've got the space.

(The Broad Street in Oxford, England, for those of us who wondered.)

Re: Confocal microscopy

#19
post #10

Used to work in the Oxford lab that developed some of the earliest confocal microscopes. I had one of the early Oxford instruments mentioned under my table. Always wondered why it didn't find it's way to a museum. Science historical artifacts aren't a huge field of history yet I guess and items only a few decades old aren't that exciting to the average person. Technology becomes ancient faster than anything else.

The History of Science Museum on Broad Street actually has a microscope collection. I can imagine they'd be interested, if they've got the space.

The do alright. Never thought to asked them although their collection is mostly brass this one's mostly plywood.

Re: Confocal microscopy

#20
post #9

Not sure why this article made it to front page, but fwiw, I used to work as a research engineer in a role where using a confocal microscope in clinical trial settings was a regular part of my job. AMA :D

Meta: I submitted it ~2 months ago because I ran into the topic for work reasons. I found the connection to Minsky reason enough since I didn't know that, and also the technology itself is of course very cool and probably not well known outside the relevant fields. The post did not get a lot of attention, but a couple of days ago I got what I think is my first offer to re-post from the admins, and since I still found…

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