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Scientists discover links between Alzheimer's disease and gut microbiota

kcl.ac.uk

11–20 of 157 posts

Re: Scientists discover links between Alzheimer's disease and gut microbiota

#11
post #4

I certainly hope they are going to replicate while knocking out one species of gut biota each time. Would be super helpful right? Edit: Experiemental design we establish indvidual colonies of each of the biota detected in our earlier work, we then recombine them in the ratios found in the original work and replicate the previous results. We then creation combinations lacking a single organism from our mix and look fo…

except our bodies already kinda do that on their own how would killing species of gut biota would helpful? helpful for whom to accomplish what?? we're headed to a future in which you have to take special pills so that the food doesn't kill you. like the glysophate and GMOs but applied against ALL life, including humans. if this is too far fetched for you then I also hope we don't get there.

> except our bodies already kinda do that on their own

do you mean it's hard to control for these parameters, because bodies will remove the controls via automatic processes?

Re: Scientists discover links between Alzheimer's disease and gut microbiota

#13
post #6

Earlier quoted context omitted.

For those that are curious and not well verse in research level biology, what kind of food, drink and lifestyle will help maintain a gut biome that prevent Alzheimer

Fatty fish, most nuts (that don't have high omega-6, which is inflammatory), fruits high in antioxidants like berries and dark fruit in general, colorful vegetable, cooking with olive/avocado/sunflower oil, *kefir* which is the champion of all good microbiota inducers As for avoiding : red meat (high in omega-6), gluten (chickpea, rice, lentil pasta instead of wheat), cooking with hydrogenated oils, preservatives, pr…

I'm a fermentation freak so I have to highlight how uncooked fermented foods like sauerkraut and the aforementioned kefir play into anti-inflammation [0].

[0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8147091/

Re: Scientists discover links between Alzheimer's disease and gut microbiota

#14
post #6

Earlier quoted context omitted.

For those that are curious and not well verse in research level biology, what kind of food, drink and lifestyle will help maintain a gut biome that prevent Alzheimer

Fatty fish, most nuts (that don't have high omega-6, which is inflammatory), fruits high in antioxidants like berries and dark fruit in general, colorful vegetable, cooking with olive/avocado/sunflower oil, *kefir* which is the champion of all good microbiota inducers As for avoiding : red meat (high in omega-6), gluten (chickpea, rice, lentil pasta instead of wheat), cooking with hydrogenated oils, preservatives, pr…

Red meat is not necessarily high in omega 6, and on the contrary grass fed meat can be high in omega 3. Also the debate is still out on whether or not omega 6 is inflammatory or not, and even omega 6 rich nuts are probably health promoting in typical quantities. From my understanding gluten is probably fine for those that don’t have a sensitivity. I think you should caveat your claims about diet since we don’t totally know to an absolute manner yet.

Re: Scientists discover links between Alzheimer's disease and gut microbiota

#15
post #6

I had to triple check the date because I was pretty sure that this was known before. Maybe it is simply the confirmation aspect of it? Edit: > Our findings reveal for the first time, that Alzheimer’s symptoms can be transferred to a healthy young organism via the gut microbiota, *confirming a causal role* of gut microbiota in Alzheimer’s disease ... From: https://faculty.sites.uci.edu/kimgreen/bio/glucocorticoids-a..…

For those that are curious and not well verse in research level biology, what kind of food, drink and lifestyle will help maintain a gut biome that prevent Alzheimer

The usual. The way we evolved: Avoid processed foods and move (i.e., exercise). Obviously, only take antibiotics when absolutely necessary.

Re: Scientists discover links between Alzheimer's disease and gut microbiota

#18

I had to triple check the date because I was pretty sure that this was known before. Maybe it is simply the confirmation aspect of it? Edit: > Our findings reveal for the first time, that Alzheimer’s symptoms can be transferred to a healthy young organism via the gut microbiota, *confirming a causal role* of gut microbiota in Alzheimer’s disease ... From: https://faculty.sites.uci.edu/kimgreen/bio/glucocorticoids-a..…

"You could sum up Alzheimer's as: Diet/Lifestyle + a congenital form of Cushing's syndrome and you have increasing glucocorticoids which imply downregulation of the PVN, less progesterone and low levels of Prolactin reducing oligodendrocyte reducing myelin sheaths. Add in APOE e4 without choline in the diet and you have accumulation of lipids to round it all out."

Can someone translate this into plain English?

Re: Scientists discover links between Alzheimer's disease and gut microbiota

#19
post #4

I certainly hope they are going to replicate while knocking out one species of gut biota each time. Would be super helpful right? Edit: Experiemental design we establish indvidual colonies of each of the biota detected in our earlier work, we then recombine them in the ratios found in the original work and replicate the previous results. We then creation combinations lacking a single organism from our mix and look fo…

except our bodies already kinda do that on their own how would killing species of gut biota would helpful? helpful for whom to accomplish what?? we're headed to a future in which you have to take special pills so that the food doesn't kill you. like the glysophate and GMOs but applied against ALL life, including humans. if this is too far fetched for you then I also hope we don't get there.

Helpful to the host so another type can flourish. Certain classes of antibiotics will wipe out species then similar but harmful types will colonize the space and you end up with autoimmune disorders.

Re: Scientists discover links between Alzheimer's disease and gut microbiota

#20
post #6

I had to triple check the date because I was pretty sure that this was known before. Maybe it is simply the confirmation aspect of it? Edit: > Our findings reveal for the first time, that Alzheimer’s symptoms can be transferred to a healthy young organism via the gut microbiota, *confirming a causal role* of gut microbiota in Alzheimer’s disease ... From: https://faculty.sites.uci.edu/kimgreen/bio/glucocorticoids-a..…

For those that are curious and not well verse in research level biology, what kind of food, drink and lifestyle will help maintain a gut biome that prevent Alzheimer

If diet had an effect on Alzheimer's, then those patients that have altered medical diets / starve at the end would show improvement, no?
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