That sounds to me like opening console and messing up with the website's JS code :D
Human embryo models grown from stem cells
11–20 of 95 posts
Re: Human embryo models grown from stem cells
#12[flagged]
Re: Human embryo models grown from stem cells
#13I used to be a researcher in NLP until not too long ago. Over the last few years, increasing pressure has been put on on everyone trying to publish papers related to training data collected through human trials to provide ethics statements as a way to ensure that certain standards are met regarding that data. Not everyone is able to see too much sense in this process, and I've heard comments from non-US colleagues th…
Why do you believe this work would not have passed an ethics review?
(your comments are a bit obscure, in a way that suggests you aren't familiar with how modern biological research is evaluated)
Re: Human embryo models grown from stem cells
#14That sounds to me like opening console and messing up with the website's JS code :D
[deleted]
Re: Human embryo models grown from stem cells
#15Earlier quoted context omitted.
The question I have is why they call it a model? It is certainly not a simulation, and although it apparently started with different components they manipulated those to behave the way the normal versions do. What would happen if they implanted it in a womb?
It’s a model because it’s not completely equivalent. Medicine has learned a great deal from studying rodents, but humans are quite different. For one thing human embryos would have already been implanted in a womb for a week at that point and a great deal of signaling occurs between embryo and the uterus.
>"For one thing human embryos would have already been implanted in a womb for a week at that point"
At what point? Implantation typically occurs 6-12 days after fertilization. This experiment starts at the equivalent of day 7. IVF is a thing.
It sounds like you're just guessing.
Edited to add, this article says "It would be illegal to implant them into a patient’s womb" which is a far cry from what you are implying, that it would be impossible.
https://www.theguardian.com/science/2023/jun/14/synthetic-hu...
Re: Human embryo models grown from stem cells
#16A team of scientists at the Weizmann Institute have successfully created an 'embryo model' that closely resembles a 14-day-old human embryo, without using sperm, eggs or womb.
The question I have is why they call it a model? It is certainly not a simulation, and although it apparently started with different components they manipulated those to behave the way the normal versions do. What would happen if they implanted it in a womb?
We don't know what will happen. Further research will provide more answers.
Re: Human embryo models grown from stem cells
#17Reducing human suffering is a noble goal and infertile couples could benefit from this research. I would rather have western world make giant leaps in this field and also set the direction of ethics here rather than just banning it and leaving it up to Russia and China to conduct this sort of research in their secret facilities.
Re: Human embryo models grown from stem cells
#18I used to be a researcher in NLP until not too long ago. Over the last few years, increasing pressure has been put on on everyone trying to publish papers related to training data collected through human trials to provide ethics statements as a way to ensure that certain standards are met regarding that data. Not everyone is able to see too much sense in this process, and I've heard comments from non-US colleagues th…
Why do you believe this work would not have passed an ethics review? (your comments are a bit obscure, in a way that suggests you aren't familiar with how modern biological research is evaluated)
I have no doubt that it passed an ethics review. I'm sorry if my comment seemed to suggest otherwise.
I suppose what I was trying to get at was a suspicion that ethics reviews in today's research landscape (not only in the medical field, but others as well) seem to me more like a lip service. And don't get me wrong, that's just an opinion, I'm sure a lot of you think otherwise.
Re: Human embryo models grown from stem cells
#19Earlier quoted context omitted.
Why do you believe this work would not have passed an ethics review? (your comments are a bit obscure, in a way that suggests you aren't familiar with how modern biological research is evaluated)
I have no doubt that it passed an ethics review. I'm sorry if my comment seemed to suggest otherwise. I suppose what I was trying to get at was a suspicion that ethics reviews in today's research landscape (not only in the medical field, but others as well) seem to me more like a lip service. And don't get me wrong, that's just an opinion, I'm sure a lot of you think otherwise.
It is true that a great deal of review is lip service. A cynic would point out that while IRBs contain an ethical review, they often exist only to absolve the university of legal or moral responsibility. The realist in me points out that ethical review has been right-shifted: now we're more likely to approve a wide range of experiments that skirt right up against the common ethical boundaries, and then let the subsequent public response determine the ethics of the action.
None of this really matters until somebody announces we can make viable embryos from stem cells or that we can bring a viable embryo to term in an artificial womb. Both of these seem to be not implausible in the next 20 years.
Re: Human embryo models grown from stem cells
#20population collapse: solved {checkmark}
warring super-solider arms race: {added to jira board}