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RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

pubmed.ncbi.nlm.nih.gov

11–20 of 31 posts

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#12

the beauty of having root access, as demonstrated by nature

This is purely speculation, but I wonder if this "root access" doesn't also come with downsides, e.g. more gene defects, which would help explain the short lifespan of most cephalopods.

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#13
post #3

the beauty of having root access, as demonstrated by nature

What a wonderful way to see it. Medicine and biohacking are simply tools to improve evolutionary fitness.

Those are week tools. If you want to greatly improve your evolutionary fitness have as many kids as possible (preferably with multiple partners). E.g. sign up as a sperm donor.

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#14

> RNA editing, a post-transcriptional process, allows the diversification of proteomes beyond the genomic blueprint; however it is infrequently used among animals for this purpose. If I had written this and showed it to my PhD advisor, I would have gotten an earful about how "what do you mean by... be specific... what about...", etc. My PI was a nitpicker. Poor fools whose papers had to be edited by him... That said,…

Your field's oversaturated. Not a criticism or anything but it's just the economics of supply and demand in life science. Take a look at how sloppy the papers are in machine learning. Nobody complains because results speak for themselves and barrels of cash are shoveled towards research simply because of the sheer utility.

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#16

> RNA editing, a post-transcriptional process, allows the diversification of proteomes beyond the genomic blueprint; however it is infrequently used among animals for this purpose. If I had written this and showed it to my PhD advisor, I would have gotten an earful about how "what do you mean by... be specific... what about...", etc. My PI was a nitpicker. Poor fools whose papers had to be edited by him... That said,…

Your field's oversaturated. Not a criticism or anything but it's just the economics of supply and demand in life science. Take a look at how sloppy the papers are in machine learning. Nobody complains because results speak for themselves and barrels of cash are shoveled towards research simply because of the sheer utility.

Writing papers is never the most utility-maximizing activity. Especially, if you're interested in cash

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#17

> RNA editing, a post-transcriptional process, allows the diversification of proteomes beyond the genomic blueprint; however it is infrequently used among animals for this purpose. If I had written this and showed it to my PhD advisor, I would have gotten an earful about how "what do you mean by... be specific... what about...", etc. My PI was a nitpicker. Poor fools whose papers had to be edited by him... That said,…

Your field's oversaturated. Not a criticism or anything but it's just the economics of supply and demand in life science. Take a look at how sloppy the papers are in machine learning. Nobody complains because results speak for themselves and barrels of cash are shoveled towards research simply because of the sheer utility.

Heh, you think there aren't sloppy papers in life science? There are guys who churn out paper weekly and no, those things aren't very impactful. I have seen plenty of crap floating around just because it has a big name attached to it at the end of a (very) long list of authors.

It is just an older field with more established "traditions" and big names that reinforce themselves over time. Regardless, I don't think it is relevant. By number, life science research is only behind the military in funding. And by utility, show me one person who does not depend on any kind of healthcare or medicine and I will show you ten people who never used machine learning products (easier to find than you think when we get out of the western hemisphere). It is banal to claim ML has more utility. It sure can make more money, but the impact on a personal level isn't comparable. Society can still function without AI but take away healthcare and you will see it goes to shit real fast.

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#18

Earlier quoted context omitted.

Your field's oversaturated. Not a criticism or anything but it's just the economics of supply and demand in life science. Take a look at how sloppy the papers are in machine learning. Nobody complains because results speak for themselves and barrels of cash are shoveled towards research simply because of the sheer utility.

Heh, you think there aren't sloppy papers in life science? There are guys who churn out paper weekly and no, those things aren't very impactful. I have seen plenty of crap floating around just because it has a big name attached to it at the end of a (very) long list of authors. It is just an older field with more established "traditions" and big names that reinforce themselves over time. Regardless, I don't think it…

I am not staying that healthcare has no value, it's just that universities produce way more life science students than what the industry can take in. At most US state schools, only a fraction of biology graduates go into healthcare and biotechnology. Most end up in totally unrelated fields, not unlike art students. This is rarely the case for engineering and CS, people do move around yes but they almost always end up working in a heavily quantitative role.

Re: RNA editing is common in behaviorally sophisticated coleoid cephalopods (2017)

#19

Earlier quoted context omitted.

Heh, you think there aren't sloppy papers in life science? There are guys who churn out paper weekly and no, those things aren't very impactful. I have seen plenty of crap floating around just because it has a big name attached to it at the end of a (very) long list of authors. It is just an older field with more established "traditions" and big names that reinforce themselves over time. Regardless, I don't think it…

I am not staying that healthcare has no value, it's just that universities produce way more life science students than what the industry can take in. At most US state schools, only a fraction of biology graduates go into healthcare and biotechnology. Most end up in totally unrelated fields, not unlike art students. This is rarely the case for engineering and CS, people do move around yes but they almost always end up…

> only a fraction of biology graduates go into healthcare and biotechnology. Most end up in totally unrelated fields, not unlike art students. This is rarely the case for engineering and CS

I find this ironic, given that my degrees are in engineering and now I am doing life science...

There is nothing wrong with people getting a degree in what they like and then find a job that make them happy. I do not categorize or draw conclusions based on the degree. I care more about what the person can do. Most of the time a CS graduate isn't that much different from a bioinformatics graduate. And a biomedical student isn't that different from an engineering student when we are trying to build that bioreactor...

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