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New study gives clues on why exercise helps with inflammation

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Re: New study gives clues on why exercise helps with inflammation

#11

Earlier quoted context omitted.

You seem to have very low reading comprehension, nowhere did I say low-dose naltrexone cures cancer. There is a youtube video about someone whose cancer was cured using low-dose naltrexone.

Dismissing an unseen Youtube video given no other evidence than that it is sourced from YT seems reasonable, rational even. The prior probability of a randomly selected YT video being trustworthy is probably a lot closer to 0 than 1.

[flagged]

Re: New study gives clues on why exercise helps with inflammation

#12

Earlier quoted context omitted.

Dismissing an unseen Youtube video given no other evidence than that it is sourced from YT seems reasonable, rational even. The prior probability of a randomly selected YT video being trustworthy is probably a lot closer to 0 than 1.

[flagged]

At this point you've edited this comment twice. First it was "autist", then "lol", now "This place is a meme. Prior probablity hahaahaa...". Who knows what it will be in the future.

None is appropriate as a response for hacker news. Please read the guidelines: https://news.ycombinator.com/newsguidelines.html

Re: New study gives clues on why exercise helps with inflammation

#13
post #10
post #8

It also seems like eating carbs is terrible for inflammation. If I go slightly over normal carb intake my knee/foot will hurt. I have screws in there and I bet it's extra sensitive to inflammation.

Any source for relevant clinical outcomes? Sounds like medically unsubstantiated anectdote.

I certainly wouldn’t extrapolate to the population at large, but I can definitively state that some carbohydrates trigger a major body-wide inflammatory response in me. There’s several plausible mechanisms by which they could trigger an immune response (past gut infection training an immune response or fodmap sensitivity being the most obvious)

Re: New study gives clues on why exercise helps with inflammation

#14
post #8

It also seems like eating carbs is terrible for inflammation. If I go slightly over normal carb intake my knee/foot will hurt. I have screws in there and I bet it's extra sensitive to inflammation.

Does this happen with any carbs?

There’s a strong link with fructose and gout.

Re: New study gives clues on why exercise helps with inflammation

#15
post #10

Earlier quoted context omitted.

Any source for relevant clinical outcomes? Sounds like medically unsubstantiated anectdote.

I certainly wouldn’t extrapolate to the population at large, but I can definitively state that some carbohydrates trigger a major body-wide inflammatory response in me. There’s several plausible mechanisms by which they could trigger an immune response (past gut infection training an immune response or fodmap sensitivity being the most obvious)

Same. Other substances too. A couple days ago I switched from white wine to red at dinnertime and my fresh mosquito bites immediately started itching when before that I didn't notice them as much.

It's not hard to believe that immune responses (allergic reactions being one end of that spectrum) are affected by the body's response to ingested substances. Especially given how strongly the gut microbiota affect blood chemistry.

Re: New study gives clues on why exercise helps with inflammation

#16
post #14
post #8

It also seems like eating carbs is terrible for inflammation. If I go slightly over normal carb intake my knee/foot will hurt. I have screws in there and I bet it's extra sensitive to inflammation.

Does this happen with any carbs? There’s a strong link with fructose and gout.

While it seems there might be an association, blaming fructose for gout seems just to be a scapegoat for a crappy diet that replaces processed meats with loads of HFCS overall

Re: New study gives clues on why exercise helps with inflammation

#17
post #14

Earlier quoted context omitted.

Does this happen with any carbs? There’s a strong link with fructose and gout.

While it seems there might be an association, blaming fructose for gout seems just to be a scapegoat for a crappy diet that replaces processed meats with loads of HFCS overall

I have my own anecdotal evidence to support my own case.

My diet is very clean. But at one point I lived in a country with an abundance of fruit and after about 2 years of indulgence I got a toe pain. Didn’t think much of it. Thought I just hit it. But then it lasted almost for a year. That’s when I got worried, did a bunch of reading. Fructose connection was a very clear one, where the traditional connection was actually not supported by evidence at all.

I reduced fruit intake significantly, and literally within days the pain went away.

And any time I eat lots of fruit a few days in a row the pain will slowly creep back in.

Re: New study gives clues on why exercise helps with inflammation

#18
post #10

Earlier quoted context omitted.

Any source for relevant clinical outcomes? Sounds like medically unsubstantiated anectdote.

I certainly wouldn’t extrapolate to the population at large, but I can definitively state that some carbohydrates trigger a major body-wide inflammatory response in me. There’s several plausible mechanisms by which they could trigger an immune response (past gut infection training an immune response or fodmap sensitivity being the most obvious)

There's certainly a lot of ways food substances can interact with bodily systems. However it can be hard to discern the exact source as different substances are correlated. Like you mention, issues with FODMAP is common, and those are often correlated with carbs. So there's a significant risk that a real effect is misattributed. Ideally you'd test if by blinding the intake, but that's often impossible or at least infeasible, so in the end we tend to latch on to some hypothesis without too much evidence.

It's also good to be aware of how strong the nocebo effect can be in this context. If you are convinced of the danger of something it can lead to significant issues. For an extreme example, severe airborne peanut allergy seems to be hard to be reproduce in controlled studies, yet there's people having significant symptoms from this, like lack of breathing etc.

Basically, when it comes to food, a lot of skepticism, including to our own experience, is often required. The risk is that we otherwise end up with unnecessary restrictive eating.

Personally I have a lot of things I "can't" eat, but even then, I try to challenge it now and then, sometimes I find something in a category I can actually eat and sometimes it turns out that I can eat it in low amounts or slowly learn to handle it.

Re: New study gives clues on why exercise helps with inflammation

#19
post #10

Earlier quoted context omitted.

Any source for relevant clinical outcomes? Sounds like medically unsubstantiated anectdote.

I certainly wouldn’t extrapolate to the population at large, but I can definitively state that some carbohydrates trigger a major body-wide inflammatory response in me. There’s several plausible mechanisms by which they could trigger an immune response (past gut infection training an immune response or fodmap sensitivity being the most obvious)

Maybe it’s not carbs, but something collocated with carbs like glyphosate.

Re: New study gives clues on why exercise helps with inflammation

#20
post #10

Earlier quoted context omitted.

Any source for relevant clinical outcomes? Sounds like medically unsubstantiated anectdote.

I certainly wouldn’t extrapolate to the population at large, but I can definitively state that some carbohydrates trigger a major body-wide inflammatory response in me. There’s several plausible mechanisms by which they could trigger an immune response (past gut infection training an immune response or fodmap sensitivity being the most obvious)

https://en.wikipedia.org/wiki/Advanced_glycation_end-product
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