> No “real programmers” write code in Assembly. This means the opposite of what she means, which is > No, “real programmers” write code in Assembly. because of the missing comma. Insisting on good spelling and grammar is not about being annoying, it's about not accidentally writing the opposite of what you want to convey :(
They mean the same thing.
> No “real programmers” write code in Assembly.
Scare quotes for sarcasm/inflection.
Would be better and more idiomatic as a singular noun.
> No, “real programmers” write code in Assembly.
The pause here just marks an interjection/response to something else. But it means the same thing (scare quotes and all).