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In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)
11–20 of 170 posts
Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)
#12https://news.ycombinator.com/item?id=31577871
This was a recent story that I wish had gained more traction.
Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)
#13You can do this at home, except for the little inconvenience that growth hormone is a scheduled drug. I wonder what the results would be with just growth hormone. Let's ask Sylvester Stallone[1] who looks great for 75 and got caught trying to get into Australia with illicit Growth Hormone a while ago[2]. [1] https://en.wikipedia.org/wiki/Sylvester_Stallone [2] https://abcnews.go.com/Health/ActiveAging/story?id=317601…
Ask Dave Polumbo
Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)
#14For anyone interested in the topic, I'd encourage reading "Lifespan" by David A. Sinclair. As someone with little to no-knowledge about aging (other than feeling the effects of aging on myself) I found it very instructive on how our aging clock works and what are some of the ongoing studies to slow down or revert aging.
Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)
#15Does anybody know if the East German sportsfolk doped HGH? According to a recent HN post, their lifespan got reduced by around a decade. https://news.ycombinator.com/item?id=31591777
Teens there were give mega doses of multiple anabolics steroids
Also hgh at a young age won't increase life span later in life anyways
Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)
#16This article is a bit old (like the other comment about missing year tag says). I think there's newer news that AKG, an easy to get and cheap supplement, has anti-aging effects with no known issues. https://www.science.org/content/article/bodybuilding-supplem...
The actual paper is here [1]. And it’s not quite as conclusive in mammals yet. But it sounds like there is a clinical trial to actually study the supplement, which is a welcome thing in the anti-aging world. I’m happy to read that this work came out of the Buck Institute in Novato, which is a solid research institution. It’s also a beautiful campus.
Disclaimer: I was there for a short stint as a postdoc a while back and not connected to this paper at all.
Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)
#17This article is a bit old (like the other comment about missing year tag says). I think there's newer news that AKG, an easy to get and cheap supplement, has anti-aging effects with no known issues. https://www.science.org/content/article/bodybuilding-supplem...
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Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)
#18Does anybody know if the East German sportsfolk doped HGH? According to a recent HN post, their lifespan got reduced by around a decade. https://news.ycombinator.com/item?id=31591777
HGH seems to increase insulin resistance so without other interventions (e.g. metformin) it may be pro-aging.
Exceptional athletes in general may not have the same lifespan as age-matched healthy counterparts so not a good population to look at.
Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)
#19Believe this was posted on hn before, but this article is in-depth on the current state
Re: In a small trial, drugs seemed to rejuvenate the body’s ‘epigenetic clock’ (2019)
#20What are the 3 ingredients? HGH, possibly metformin and what else? The article does not clearly state.