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Man given genetically modified pig heart dies

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Re: Man given genetically modified pig heart dies

#13
Related:

US man who got first pig heart transplant dies after 2 months - https://news.ycombinator.com/item?id=30615375 - March 2022 (3 comments)

Two weeks later David Bennett is alive, his pig’s heart beating soundly - https://news.ycombinator.com/item?id=30080472 - Jan 2022 (490 comments)

The doctor behind the first pig-to-human heart transplant - https://news.ycombinator.com/item?id=30044630 - Jan 2022 (3 comments)

In a First, Man Receives a Heart from a Genetically Altered Pig - https://news.ycombinator.com/item?id=29900921 - Jan 2022 (2 comments)

U.S. surgeons transplant pig heart into human patient - https://news.ycombinator.com/item?id=29882912 - Jan 2022 (701 comments)

Re: Man given genetically modified pig heart dies

#15

He lasted 2 months. For reference, artificial hearts generally do 130 days - (2018) https://syncardia.com/patients/media/blog/2018/08/seven-thin... with some notable outliers that live for years, and human to human transplant is about 9 years. Usually it's some related systemic problem that kills you under these conditions eg consistent brain clotting causing stroke or organ failure due to drug cocktails.

> He had already been bedridden for six weeks leading up to the surgery, attached to a machine which was keeping him alive.

Slightly less.

Re: Man given genetically modified pig heart dies

#16

My friend was a member of the transplant team at Johns Hopkins. "They" said he was near multiple organ failure prior to the transplant. And he survived significantly longer than expected. Recovery under those circumstances was a very long shot already. Kudos to him for undergoing the procedure, and furthering the research. Condolences to he and his family.

Which is probably how they got approval to do a pig heart transplant in the first place since he would never get on the transplant list.

Re: Man given genetically modified pig heart dies

#17

He lasted 2 months. For reference, artificial hearts generally do 130 days - (2018) https://syncardia.com/patients/media/blog/2018/08/seven-thin... with some notable outliers that live for years, and human to human transplant is about 9 years. Usually it's some related systemic problem that kills you under these conditions eg consistent brain clotting causing stroke or organ failure due to drug cocktails.

Heart transplant recipients survive 15 years on average: https://en.wikipedia.org/wiki/Heart_transplantation

Re: Man given genetically modified pig heart dies

#18
post #4
post #2

“Currently 17 people die every day in the US waiting for a transplant, with more than 100,000 reportedly on the waiting list.” David Bennett was only 57. Heart disease, and related issues are a big problem. While I’m hopeful for this technology, I wish there was a way for people to see heart issues coming much earlier in life so they can attempt to treat, or delay, the problem.

Or, change the way they live, work less and enjoy what little life they have ahead?

How would you apply this to a child, or convey it to their parents?

The procedure has a profound effect on the family that receives the heart and on the donor family. Hearing donor family members describe what it’s like knowing their child’s heart is still beating somewhere is something you don’t forget.

Re: Man given genetically modified pig heart dies

#19
post #2

“Currently 17 people die every day in the US waiting for a transplant, with more than 100,000 reportedly on the waiting list.” David Bennett was only 57. Heart disease, and related issues are a big problem. While I’m hopeful for this technology, I wish there was a way for people to see heart issues coming much earlier in life so they can attempt to treat, or delay, the problem.

To everyone that reads this:

If you've not had a checkup in the last year go and get one! It'll be included on your health insurance and the blood draw will include things like if you have high cholesterol.

Re: Man given genetically modified pig heart dies

#20
post #4

Earlier quoted context omitted.

Or, change the way they live, work less and enjoy what little life they have ahead?

your view indicates a lack of empathy for folks that live differently than you

I don't mean to be callous by this comment but if you mean "live differently" as living unhealthy well I have a problem with this. People that live in unhealthy ways cause all sorts of grief to others as well as financial loss. It is not right that I have to pay for people that decide to essentially eat themselves to death; it is not right that my wife and I had to care for my mother for months because she decided to eat herself to death. Heart disease and diabetes are all too common "paid" for by others - they should choose differently and while we can't make them choose differently we should for sure tell them that their choices are not "o.k.".
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