Inhaled Vaccine Delivers Broad Protection Against SARS-CoV-2 • Hacker News Board

Re: Inhaled Vaccine Delivers Broad Protection Against SARS-CoV-2

#11

Post by sschueller » Wed, Feb 16, 2022, 3:49 PM UTC

onion2k wrote: post #5

This is what they put in chemtrails. ;)

Just mix it into the tear gas canisters at the protests. Problem solved, either the anti vaxxers stay home or get vaxxed.

Re: Inhaled Vaccine Delivers Broad Protection Against SARS-CoV-2

#12

Post by dang » Wed, Feb 16, 2022, 3:50 PM UTC

calebm wrote: post #4

Quoted post unavailable.

Please don't post unsubstantive and/or flamebait comments. It leads to worse threads.

https://news.ycombinator.com/newsguidelines.html

Re: Inhaled Vaccine Delivers Broad Protection Against SARS-CoV-2

#13

Post by xiphias2 » Wed, Feb 16, 2022, 3:50 PM UTC

What is the main reason that inhaled vaccines are not in use today for flu for example? Is there some new technological breakthrough for delivery that was needed?

Re: Inhaled Vaccine Delivers Broad Protection Against SARS-CoV-2

#14

Post by questiondev » Wed, Feb 16, 2022, 3:52 PM UTC

swader999 wrote: post #9

petsounds wrote: post #8

Earlier quoted context omitted.

There are ~10k people dying of COVID every day since Omicron was detected, sounds like we could use a better one

Of or with?

depends on dialect of english

Re: Inhaled Vaccine Delivers Broad Protection Against SARS-CoV-2

#15

Post by kwantam » Wed, Feb 16, 2022, 3:52 PM UTC

calebm wrote: post #4

Quoted post unavailable.

It's a tempting sound bite, but it's wrong.

First, a real vaccine is designed to be much safer than the disease it protects against (compare extremely rare incidence of vaccine side effects with extremely common incidence of hospitalization for infection). What would be the point otherwise?

Second, in the case of COVID variants prior to Omicron, infection is 5x less effective than vaccination at protecting against future infection: https://www.cdc.gov/media/releases/2021/s1029-Vaccination-Of...

Re: Inhaled Vaccine Delivers Broad Protection Against SARS-CoV-2

#16

Post by sleepingadmin » Wed, Feb 16, 2022, 3:54 PM UTC

Does it prevent infection? If not, it's not a vaccine.

Re: Inhaled Vaccine Delivers Broad Protection Against SARS-CoV-2

#17

Post by kwantam » Wed, Feb 16, 2022, 3:55 PM UTC

xiphias2 wrote: post #13

What is the main reason that inhaled vaccines are not in use today for flu for example? Is there some new technological breakthrough for delivery that was needed?

They are! Inhaled flu vaccines are generally live attenuated virus, which isn't recommended for everyone but is perfectly effective for a large segment of the population:

https://www.cdc.gov/flu/prevent/nasalspray.htm

Re: Inhaled Vaccine Delivers Broad Protection Against SARS-CoV-2

#18

Post by consumer451 » Wed, Feb 16, 2022, 3:57 PM UTC

xiphias2 wrote: post #13

What is the main reason that inhaled vaccines are not in use today for flu for example? Is there some new technological breakthrough for delivery that was needed?

From a lay person's point of view, I am trying to imagine if there would be significant extra mass required to distribute a billion inhalable vs injectable vaccines. It seems like there would be additional mass and volume. Could that be one reason?

Re: Inhaled Vaccine Delivers Broad Protection Against SARS-CoV-2

#19

Post by vmception » Wed, Feb 16, 2022, 4:06 PM UTC

calebm wrote: post #4

Quoted post unavailable.

I get it, because the similarity is that it is a weakened version of the virus, just like how our non-mRNA vaccines have been structured

Re: Inhaled Vaccine Delivers Broad Protection Against SARS-CoV-2

#20

Post by prohobo » Wed, Feb 16, 2022, 4:10 PM UTC

sleepingadmin wrote: post #16

Does it prevent infection? If not, it's not a vaccine.

This shouldn't be downvoted, it's true.

There's nothing wrong with creating good drugs and therapies, and this looks cool, but if it doesn't stop transmission it's literally not a vaccine.

EDIT: I'm wrong. I would have been right for the wrong reasons in 2018, but now vaccines are "any substance that generates antibodies that produce immunity to disease".