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Theses on Sleep

guzey.com

11–20 of 102 posts

Re: Theses on Sleep

#11
post #3

This essay, convinced me that people with no domain specific knowledge can cherry-pick ideas to support any BS they want

Here is another one of Alexey’s essays that might convince you that people with tons of domain-specific knowledge (and credentials too!) can also cherry-pick ideas to support any BS they want.

https://guzey.com/books/why-we-sleep/

Matthew Walker's "Why We Sleep" Is Riddled with Scientific and Factual Errors

Re: Theses on Sleep

#13
post #9

A lot of this stuff matches my experience. I'm a classic night owl and occasionally subject myself to acute sleep deprivation (< 3-4 hours of sleep). Typically the next day I'm in weirdly good humor, slightly manic, and feel as if my senses have been heightened. My girlfriend thinks I'm crazy for saying this, but I enjoy the feeling. If the sleep deprivation turns into multiple days, I begin to become sluggish and ir…

As a night owl and an introvert, there's this perverse feedback loop where I'm incentivized to be underslept before an important presentation, because the slight good humor / mania / heightened senses (and, I would add, a mild numbness to peoples' judgments about me) help me do a better job of the presentation.

Of course, I'm not advocating that people be totally loopy! But there's a weird Ballmer peak-esque [1] effect.

[1] https://xkcd.com/323/

Re: Theses on Sleep

#14
> I have been able to find exactly one pre-registered experiment of the impact of prolonged sleep deprivation on cognition. It was published by economists from Harvard and MIT in 2020 and its pre-registered analysis found null effects of sleep on all variables of interest Bessone P, Rao G, Schilbach F, Schofield H, Toma M. The economic consequences of increasing sleep among the urban poor. The Quarterly Journal of Economics. 2021 Aug;136(3):1887-941.(the authors changed analysis post-hoc and fished out some significant effects. Notably, they put the post-hoc results into the abstract but decided not to mention the null-preregistered results there or anywhere else in the paper explicitly ).

This is the highest quality of research from the most fancied universities, and it was pre-registered (the gold standard of oversight). And even they were dishonest with the results. For me, personally, this single paragraph is enough to shut the door on all (all) psychology research.

Re: Theses on Sleep

#15
Do not spend time reading it. From the article:

"I have no trust in sleep scientists

Why do I bother with all of this theorizing? Why do I think I can discover something about sleep that thousands of them couldn’t discover over many decades?

The reason is that I have approximately 0 trust in the integrity of the field of sleep science."

By the way, he criticizes the book: "Why we sleep". Sure the book exaggerates, but it shouldn't be completely disqualified. BTW, if you like this book, you will probably like Oracle of the Night: https://www.theguardian.com/books/2022/jan/07/the-oracle-of-...

Re: Theses on Sleep

#16
post #15

Do not spend time reading it. From the article: "I have no trust in sleep scientists Why do I bother with all of this theorizing? Why do I think I can discover something about sleep that thousands of them couldn’t discover over many decades? The reason is that I have approximately 0 trust in the integrity of the field of sleep science." By the way, he criticizes the book: "Why we sleep". Sure the book exaggerates, bu…

For those interested, here's my critique of sleep science (https://guzey.com/theses-on-sleep/#our-priors-about-sleep-re...):

>Do you believe in power-posing? In ego depletion? In hungry judges and brain training? [1]

>If the answer is no, then your priors for our knowledge about sleep should be weak because “sleep science” is mostly just rebranded cognitive psychology, with the vast majority of it being small-n, not pre-registered, p-hacked experiments.

>I have been able to find exactly one pre-registered experiment of the impact of prolonged sleep deprivation on cognition. It was published by economists from Harvard and MIT in 2020 and its pre-registered analysis found null effects of sleep on all variables of interest [2] (the authors changed analysis post-hoc and fished out some significant effects. Notably, they put the post-hoc results into the abstract but decided not to mention the null-preregistered results there or anywhere else in the paper explicitly).

>So why has sleep research not been facing a severe replication crisis, similar to psychology?

>First, compared to psychology, where you just have people fill out questionnaires, sleep research is slow, relatively expensive, and requires specialized equipment (e.g. EEG, actigraphs). So skeptical outsiders go for easier targets (like social psychology) while the insiders keep doing the same shoddy experiments because they need to keep their careers going somehow.

>Second, imagine if sleep researchers had conclusively shown that sleep is not important for memory, health, etc. – would they get any funding? No. Their jobs are literally predicated on convincing the NIH and other grantmakers that sleep is important. As Patrick McKenzie notes [3], “If you want a problem solved make it someone’s project. If you want it managed make it someone’s job.”

>Even in medicine, without pre-registered RCTs truth is extremely difficult to come by, with more than one half [4] of high-impact cancer papers failing to be replicated, and with one half of RCTs without pre-registration of positive outcomes being spun [5] by researchers as providing benefit when there’s none. And this is in medicine, which is infinitely more consequential and rigorous than psychology.

And here's my critique of Why We Sleep, which the author of the comment above decided to omit for some reason:

>Here are just a few of biggest issues (there were many more) with the book.

>1. Walker wrote: “Routinely sleeping less than six or seven hours a night demolishes your immune system, more than doubling your risk of cancer”, despite there being no evidence that cancer in general and sleep are related. There are obviously no RCTs on this, and, in fact, there’s not even a correlation between general cancer risk and sleep duration. [6]

>2. Walker falsified a graph from an academic study in the book. [7]

>3. Walker outright fakes data to support his “sleep epidemic” argument. The data on sleep duration Walker presents on the graph below simply does not exist [8]

[1] https://www.gleech.org/psych

[2] https://economics.mit.edu/files/16994

[3] https://twitter.com/patio11/status/1223695673742151680

[4] https://www.science.org/content/article/more-half-high-impac...

[5] https://journals.plos.org/plosone/article?id=10.1371/journal...

[6] https://guzey.com/books/why-we-sleep/#also-no----sleeping-le...

[7] https://guzey.com/books/why-we-sleep/#appendix-what-do-you-d...

[8] https://guzey.com/books/why-we-sleep/#ok-even-if-the-who-nev...

Re: Theses on Sleep

#17
post #15

Do not spend time reading it. From the article: "I have no trust in sleep scientists Why do I bother with all of this theorizing? Why do I think I can discover something about sleep that thousands of them couldn’t discover over many decades? The reason is that I have approximately 0 trust in the integrity of the field of sleep science." By the way, he criticizes the book: "Why we sleep". Sure the book exaggerates, bu…

Just a nitpick. In your quote it looks like the author is writing "I have no trust in sleep scientists [because] I have approximately 0 trust in the integrity of the field of sleep science".

However, the first "I have no trust in sleep scientists" is a heading, which makes the rest sound less ridiculous - the "because" part simply comes after the part you quoted.

Re: Theses on Sleep

#18
post #15

Do not spend time reading it. From the article: "I have no trust in sleep scientists Why do I bother with all of this theorizing? Why do I think I can discover something about sleep that thousands of them couldn’t discover over many decades? The reason is that I have approximately 0 trust in the integrity of the field of sleep science." By the way, he criticizes the book: "Why we sleep". Sure the book exaggerates, bu…

funny, this makes me even more desirous to read it

Re: Theses on Sleep

#19
post #5

Earlier quoted context omitted.

https://twitter.com/alexeyguzey/status/1490664815039234051 I think the author has been pretty forthright in seeking critiques from professional sleep researchers and neuroscientists.

I will post random theories about the nature of the universe and I'll tweet that I'm expecting critiques from physicists about my theory. Damn, should look good on a resume.

Hilarious. Except for the fact that a bunch of neuroscientists actually read my draft and gave me comments a lot of which I incorporated in the essay, e.g. https://guzey.com/theses-on-sleep/#appendix-philipp-streiche...

Re: Theses on Sleep

#20

I like that this challenges some assumptions, but it does very little to discredit the AMPLE research in the area. Other than to say, let's not trust old research, which is kind of a gas-lighty way to look at it.

I'm curious - what do you believe I should've done? How do you discredit a p-hacked small-n experiment, aside from noting that it should not be trusted a priori due to the extreme bias of the results expected from such kind of studies?
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