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Israel Finds Fourth Covid Booster Is Ineffective

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Re: Israel Finds Fourth Covid Booster Is Ineffective

#11

Post by top_post »

not2b wrote: post #5

There are two separate questions: Does an extra booster prevent infection? Does an extra booster reduce hospitalizations and deaths? Seems this study only addressed the first question. But instead of giving a fourth shot based on the OG Covid, seems an updated version based on omicron, delta, and any new variants of concern would be a better idea.

I can't for the life of me understand why your last statement isn't what the world is driving for at the moment. mRNA vaccines are easily(-ish) updated, so punch out an Omicron specific dose and get on with the regular single/dual (if needed) regime.

It seems strange we'd opt for 3-4-5 shots given the benefit of mRNA was its ease of creation and modification.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#12

Post by jleyank »

Then they just rush-approve the mRNA vaccines with the modified payloads for Omicron and possibly Delta. The same delivery systems, merely different mRNA sequences, so I would think there's reasonable chance the (side)effects are the same. I thought this is already happening on the normal timeline.

And there's a whole lot of vaccines coming on line that use different delivery systems and/or targets. There's a chance that one of them is effective vs. Omicron. If so, there's a number of govts that have gobs of money and the ability to direct what gets manufactured if they so wish. Others can break patents on a national security justification and manufacture locally.

Whether people will take them is a different question, but Darwin might keep having some effect with this. As others have said, the ultimate goal is keeping people out of hospital not from sniffling.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#13

Post by momirlan »

ars wrote: post #3

Ineffective for Omicron . It still helps immunity in general, so is recommended for immunocompromized people and others with low immunity, most people don't need it though, the gain isn't enough to matter for them.

What is "immunity in general" for you ? This shot is not vitamin C

Re: Israel Finds Fourth Covid Booster Is Ineffective

#14

Post by goalieca »

cblconfederate wrote: post #8
MichaelMoser123 wrote: post #6

I am living in Israel, i doubt that it is possible to state anything definitively on the subject: regulations and decissions are being changed on a daily basis. I am not a healthcare specialist, however all this is giving the impression of being one big mess...

I think it can definitely be stated that having weekly decisions about something as serious and possibly long-lasting as vaccinations are a bad omen. Especially if we consider possible adverse effects in children we should instead opt for partial lockdowns at least temporarily to stem the wave

Lockdowns have known serious and long lasting effects.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#15

Post by ummonk »

> the amount of antibodies returns to the level it was after the third vaccine, not more. It’s nice, but it’s not what we expect from a booster

So basically it doesn’t confer any long term benefits - the only value from it would be if you want to keep your circulating antibodies high by perpetually boosting on a regular interval.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#16

Post by mandmandam »

loeg wrote: post #9

If this source is legit — and I’ve never heard of it, so who knows — the headline is missing a pretty significant word: > A fourth COVID-19 booster mRNA vaccine has proven ineffective against Omicron infection

... That's literally the first line of the article.

Handy tip: When the article provides its source material and even links to it, it doesn't really matter whether you heard of it before or not.

On top of that: "Meanwhile, the European Medicines Agency (EMA) cautioned last week that there was no evidence to back a fourth booster, warning that repeat boosters every four months might actually weaken people’s immune systems". The source for that is also linked in the article.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#17

Post by mandmandam »

ummonk wrote: post #15

> the amount of antibodies returns to the level it was after the third vaccine, not more. It’s nice, but it’s not what we expect from a booster So basically it doesn’t confer any long term benefits - the only value from it would be if you want to keep your circulating antibodies high by perpetually boosting on a regular interval.

> perpetually boosting on a regular interval.

... Which is expressly advised against by the EMA, as linked in the article.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#18

Post by version_five »

If I understand correctly, israel mandates a third shot (to do normal stuff), as do many places in north america, either now or soon. And I can only imagine many people would be happy to mandate a fourth as soon as possible.

What I find most frustrating is that politicians are happy to make these mandates live, during an ongoing situation where we actually don't know a lot about how effective things are (and in the case of the latest variant, we know they are not effective). It's one thing to provide treatment to people that want it, and to share the latest thinking and advice. But it becomes pretty ridiculous when the latest musings go unfiltered into mandates.

I read there is an omicron specific vaccine that will be ready in a couple months. Will that then immediately be forced on everyone, even if they've already had their 3-4 shots? What if we invent another thing?

Vaccines make sense, but real time forcing people to take them as soon as they're invented doesn't. I have my three shots, but I'm terrified now that the precident is set that a government can force me to take something that I might not want to. When was the last time anyone actually trusted a government?

Re: Israel Finds Fourth Covid Booster Is Ineffective

#19

Post by loyukfai »

top_post wrote: post #11
not2b wrote: post #5

There are two separate questions: Does an extra booster prevent infection? Does an extra booster reduce hospitalizations and deaths? Seems this study only addressed the first question. But instead of giving a fourth shot based on the OG Covid, seems an updated version based on omicron, delta, and any new variants of concern would be a better idea.

I can't for the life of me understand why your last statement isn't what the world is driving for at the moment. mRNA vaccines are easily(-ish) updated, so punch out an Omicron specific dose and get on with the regular single/dual (if needed) regime. It seems strange we'd opt for 3-4-5 shots given the benefit of mRNA was its ease of creation and modification.

Both Pfizer and Moderna, at the minimum, have been developing, or already developed, a version of COVID vaccine targeting Omicron.

Re: Israel Finds Fourth Covid Booster Is Ineffective

#20

Post by mandmandam »

vmception wrote: post #4

Shot from seasonal ailment two seasons ago not effective this season, here is the most random news source you can find to tell this obvious truth

For a "random news source", it sure links to the source material better than "random corporate news source".

Weird how so many people are fixated on that, given that it is trivial to click on any of the links provided.

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