Interesting. It’s not double blind and I’m not sure how practical this is but it does cast a lot of doubt on the conclusion that ivermectin doesn’t do anything unless the dose is lethal.
Ivermectin Prophylaxis Used for Covid-19 (Peer-Reviewed)
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Re: Ivermectin Prophylaxis Used for Covid-19 (Peer-Reviewed)
#12In interpreting this result, one should keep in mind that an active parasite infection produces worse results for respiratory infections of all kinds. Taking ivermectin reduces parasite load.
The size and location of the study suggests that reporting of COVID-19 infections was by presentation, meaning asymptomatic or minimal infections were probably not counted.
tl;dr: These results will probably not translate well to places without pervasive parasite infestation. Wearing an N95 mask has a much larger protective effect than taking ivermectin, in any case, even there.
Re: Ivermectin Prophylaxis Used for Covid-19 (Peer-Reviewed)
#13Makes sense in Brazil, but is it applicable to the US or other Western nations?
Not when we have extremely safe, highly effective vaccines.
But in places where they aren't available it could be interesting especially if Omicron is the dominant variant and reducing transmission isn't of much use (which Ivermectin doesn't help with).
Re: Ivermectin Prophylaxis Used for Covid-19 (Peer-Reviewed)
#14Interesting. It’s not double blind and I’m not sure how practical this is but it does cast a lot of doubt on the conclusion that ivermectin doesn’t do anything unless the dose is lethal.
Ivermectin affects parasite load, and parasite load affects outcomes of acute respiratory infection.
The effect size is smaller than from wearing a good mask.
Re: Ivermectin Prophylaxis Used for Covid-19 (Peer-Reviewed)
#15These seems like a pretty thorough study... is it OK for people to talk about Ivermectin now or are they still going to censor and ban accounts?
Well, I don't think HN will ban accounts for that. They ban accounts for being mean or starting flamewars. Being republican is NOT a reason for bans here.
Genuinely curious why alignment with this drug is so republican. Seems like the kind of thing that ought to be bipartisan if it's arguably progressive.
Re: Ivermectin Prophylaxis Used for Covid-19 (Peer-Reviewed)
#16These seems like a pretty thorough study... is it OK for people to talk about Ivermectin now or are they still going to censor and ban accounts?
Well, I don't think HN will ban accounts for that. They ban accounts for being mean or starting flamewars. Being republican is NOT a reason for bans here.
No post body was provided.
Re: Ivermectin Prophylaxis Used for Covid-19 (Peer-Reviewed)
#17Quoted post unavailable.
Pre-infection prophylaxis is not the same as treatment for infection. That's where a large number of people had things wrong.
Re: Ivermectin Prophylaxis Used for Covid-19 (Peer-Reviewed)
#18Quoted post unavailable.
Why would they apologise ?
People were literally taking the horse de-wormer formulations because they couldn't buy it legally.
Re: Ivermectin Prophylaxis Used for Covid-19 (Peer-Reviewed)
#19Quoted post unavailable.
No, he was not right. The correct interpretation is, "where parasite infections are endemic, treat that and your health will benefit." And, wear your mask.
Re: Ivermectin Prophylaxis Used for Covid-19 (Peer-Reviewed)
#20> SIQ™ is a predictive measure of scientific quality.
> How can I improve my article's SIQ™?
> Telling your friends, colleagues and advisors to review the article on Cureus
> Cureus offers a social media promotional add-on, or boost, for eligible published articles at an additional cost.
So this site is like PubMed but with payola?