Booster jabs 'massively' strengthen the body’s defenses against Covid • Hacker News Board

Re: Booster jabs 'massively' strengthen the body’s defenses against Covid

#11

Post by rsynnott » Fri, Dec 03, 2021, 4:42 PM UTC

anramon wrote: post #7

So, saying that vaccination should be primarily and aggressively focused on people with comorbilities can be "misinformation" but saying that booster jabs "massively" strengthen bodys's defense against covid is completely accuarate and acceptable. I think we are really getting into a point of no return here, i'm actually seriously worried about all this.

> So, saying that vaccination should be primarily and aggressively focused on people with comorbilities can be "misinformation"

Eh? That's not misinformation and has been the policy of most governments, more or less. Now, it would be misinformation to suggest that it doesn't need to be given to anyone else.

> but saying that booster jabs "massively" strengthen bodys's defense against covid is completely accuarate and acceptable.

That is what the studies say (obviously, 'massively' is editorialisation).

I'm not sure what your point is, here?

Re: Booster jabs 'massively' strengthen the body’s defenses against Covid

#12

Post by rsynnott » Fri, Dec 03, 2021, 4:43 PM UTC

guilhas wrote: post #3

The vaccine initially 90%+ protection was so good we were all going to be "free", amazing...

Versus the variants available at the time, yes. Unfortunately, the people running the studies couldn't get the budget for a time machine to see what would be happening in late 2021.

Note that the possibility of future variants was certainly raised at the time; it was never any secret that this was an evolving situation.

Re: Booster jabs 'massively' strengthen the body’s defenses against Covid

#13

Post by rsynnott » Fri, Dec 03, 2021, 4:45 PM UTC

_red wrote: post #2

Imagine needing to get boosters every 3 months and being so insane you think its working....

I mean, hopefully we don't end up in that situation, but it would still clearly be better than _not_ having the boosters, if what's where we do end up.

Re: Booster jabs 'massively' strengthen the body’s defenses against Covid

#14

Post by giardini » Fri, Dec 03, 2021, 4:53 PM UTC

disabled wrote: post #8

Yep. Getting boosted (getting a booster) confers secondary immune response. The initial jabs only confer primary immune response. See this for more info: https://bio.libretexts.org/Bookshelves/Microbiology/Book%3A_...

I find the use of "primary" and "secondary immune response" to be misleading. FWIW

"As Hopkins Medicines suggests, the third dose of the mRNA COVID-19 vaccines- Pfizer and Moderna- is *identical* to its first two doses. "[emphasis mine]

From

https://www.republicworld.com/technology-news/science/is-pfi...

Re: Booster jabs 'massively' strengthen the body’s defenses against Covid

#15

Post by tinus_hn » Fri, Dec 03, 2021, 5:59 PM UTC

disabled wrote: post #8

Yep. Getting boosted (getting a booster) confers secondary immune response. The initial jabs only confer primary immune response. See this for more info: https://bio.libretexts.org/Bookshelves/Microbiology/Book%3A_...

So what kind of response are we going to get from the next booster shots that have already been announced? The tertiary immune response?

Re: Booster jabs 'massively' strengthen the body’s defenses against Covid

#16

Post by disabled » Fri, Dec 03, 2021, 6:49 PM UTC

tinus_hn wrote: post #15

disabled wrote: post #8

Yep. Getting boosted (getting a booster) confers secondary immune response. The initial jabs only confer primary immune response. See this for more info: https://bio.libretexts.org/Bookshelves/Microbiology/Book%3A_...

So what kind of response are we going to get from the next booster shots that have already been announced? The tertiary immune response?

We don't know if an omicron specific booster will actually work due to something called "Original Antigenic Sin". For more information, consult this: https://www.sciencedirect.com/science/article/abs/pii/S08968...

If you are eligible for a booster, then you should get one ASAP. The original coronavirus vaccine antibodies present in your body will cross-react, to a certain degree, with omicron.

Re: Booster jabs 'massively' strengthen the body’s defenses against Covid

#17

Post by impendingchange » Sat, Dec 04, 2021, 5:17 AM UTC

rsynnott wrote: post #11

anramon wrote: post #7

So, saying that vaccination should be primarily and aggressively focused on people with comorbilities can be "misinformation" but saying that booster jabs "massively" strengthen bodys's defense against covid is completely accuarate and acceptable. I think we are really getting into a point of no return here, i'm actually seriously worried about all this.

> So, saying that vaccination should be primarily and aggressively focused on people with comorbilities can be "misinformation" Eh? That's not misinformation and has been the policy of most governments, more or less. Now, it would be misinformation to suggest that it doesn't need to be given to anyone else. > but saying that booster jabs "massively" strengthen bodys's defense against covid is completely accuarate and…

Perhaps that editorializing seems to push a narrative, when the Lancet study doesn't contain the word "massively" at all.

To quote the single-sentence summary of the study, "All study vaccines boosted antibody and neutralising responses after ChAd/ChAd initial course and all except one after BNT/BNT, with no safety concerns", flies in the face of what most people anecdotally know with regards to vaccine safety, which could be interpreted as "pushing a narrative".

https://openvaers.com/

Re: Booster jabs 'massively' strengthen the body’s defenses against Covid

#18

Post by nojokes » Sat, Dec 04, 2021, 12:51 PM UTC

_red wrote: post #2

Imagine needing to get boosters every 3 months and being so insane you think its working....

Is this comment about UK decision to give boosters after 3 months from last vaccination?

I think there is big misconception about boosters and Delta. People appear to assume that there is some time after what vaccines loose effectiveness against Delta.

I see it rather as assumption that 1 shot should work against Wuhan variant. Well, it does not so does not 2 shots against Delta. Waiting period is irrelevant. It is only a compromise between mounting a better immune response from time difference and risk of infection.