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Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

fiercebiotech.com

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Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#11

Post by jeffbee »

brink wrote: post #5

> There were six hospitalizations and no deaths among the 607 patients who received Paxlovid within five days of symptom onset, compared to 41 hospitalizations and 10 deaths in the placebo cohort. How does this work? You sign up for the program when you're sick and you might get meds that help you? That would really suck if a loved one was in the program and died because they happened to get the placebo.

They randomly assign people to the control or treatment cohort. Don’t forget there’s also the chance that the treatment gives patients liver cancer or some other yet-unknown adverse outcomes.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#12

Post by kenjackson »

brink wrote: post #5

> There were six hospitalizations and no deaths among the 607 patients who received Paxlovid within five days of symptom onset, compared to 41 hospitalizations and 10 deaths in the placebo cohort. How does this work? You sign up for the program when you're sick and you might get meds that help you? That would really suck if a loved one was in the program and died because they happened to get the placebo.

It’s a trial. That’s not how they distribute it outside of a trial.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#13

Post by phh »

> Pfizer used data on patients who were treated within three days of symptom onset as the headline finding in its press release

> There were six hospitalizations and no deaths among the 607 patients who received Paxlovid within five days of symptom onset, compared to 41 hospitalizations and 10 deaths in the placebo cohort.

> Like Merck, Pfizer excluded people vaccinated against COVID-19 from its late-phase study.

No pricing information. I'm worried that "3 days after symptoms onset" is too short to be usable in real-life, but I could be wrong.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#14

Post by merpnderp »

cbtacy wrote: post #8
rafale wrote: post #2

So as good as a vaccine basically?

As long as your definition of "good" doesn't include public health and you know "not killing other people", sure... it's as "good".

People should get vaccinated. But at this point making claims that the vaccinated don't spread covid is not supported by the science.

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#16

Post by tasogare »

Glad I waited instead of taking part in an experiment trial. There was an "easy" solution after all... I wonder what is the gotcha though, since it's a Pfizer study. Maybe something like selling a known molecule 10 times more expensive than before after rebranding it for the new usage?

Re: Pfizer's oral Covid-19 antiviral cuts hospitalization, death by 85%

#19

Post by shusaku »

I think it’s hard to overstate what a big deal this is for science. This is a completely novel molecule that appears effective as an antiviral. This would a huge achievement for the field of drug design, and will hopefully lead to all kinds of great medicine.
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